可兴奋膜与上皮细胞中钠通道的相似性。
Similarities between sodium channels in excitable membranes and in epithelia.
作者信息
Cuthbert A W
出版信息
Experientia. 1976 Oct 15;32(10):1321-3. doi: 10.1007/BF01953117.
PMID:10179
Abstract
The inhibitory effects of the pyrazine derivative, amiloride, on sodium transport in an amphibian epithelium has been studied as a function of pH. It is concluded that the charged (guanidinium) group interacts with a negatively charged acid grouping in the membrane. Similarities between sodium channels in excitable membranes and epithelia are highlighted.
摘要
已对吡嗪衍生物氨氯吡咪对两栖动物上皮中钠转运的抑制作用作为pH的函数进行了研究。得出的结论是，带电荷的（胍基）基团与膜中带负电荷的酸性基团相互作用。突出了可兴奋膜和上皮中钠通道之间的相似性。
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