Duch-Samper A M, Chaqués-Alepuz V, Menezo J L, Hurtado-Sarrió M
Service of Ophthalmology, Arnau de Vilanova Hospital, Valencia, Spain.
Curr Opin Ophthalmol. 1998 Jun;9(3):59-65. doi: 10.1097/00055735-199806000-00011.
Endophthalmitis following open-globe injuries is caused by a specific range of microorganisms, of which Bacillus sp. and coagulase-negative Staphylococcus are the most frequent. Risk factors include the presence of an intraocular foreign body, injury inflicted by organic material, delay in surgery, and the type of wound involved. Despite important advances in medical and surgical management, this type of endophthalmitis continues to pose a poor prognosis. In this sense, we consider prevention to be the best approach. We report our protocols for the prevention and treatment of endophthalmitis following open-globe injuries, based on recent experimental studies on the ocular pharmacokinetics of antibiotics and on multicenter studies of the treatment of endophthalmitis.
开放性眼球损伤后发生的眼内炎是由特定种类的微生物引起的，其中芽孢杆菌属和凝固酶阴性葡萄球菌最为常见。危险因素包括眼内异物的存在、有机材料造成的损伤、手术延迟以及伤口类型。尽管在药物和手术治疗方面取得了重要进展，但这种类型的眼内炎预后仍然很差。从这个意义上说，我们认为预防是最佳方法。我们根据近期关于抗生素眼内药代动力学的实验研究以及眼内炎治疗的多中心研究，报告我们开放性眼球损伤后眼内炎的预防和治疗方案。
