Mulder C L, de Vroome E M, van Griensven G J, Antoni M H, Sandfort T G
Helen Dowling Institute for Biopsychosocial Medicine, Rotterdam, The Netherlands.
Health Psychol. 1999 Mar;18(2):107-13. doi: 10.1037//0278-6133.18.2.107.
The present study prospectively investigated the relation between avoidance coping and active cognitive and behavioral coping and the progression of HIV infection over 7 years in 181 gay men. Findings revealed that for a number of medical and behavioral factors, (a) avoidance coping predicted a lower rate of decline in CD4 cells, (b) the proportional hazard (PH) attributable to avoidance of developing a syncytium-inducing HIV variant was 0.72 (95% confidence interval [CI]: 0.53 - 0.99, p < .05), and (c) the PH attributable to avoidance of dropping below 200 CD4 cells/microl was 0.66 (95% CI: 0.50 - 0.89, p < .01). Avoidance coping was not related to the development of AIDS-defining clinical symptoms. Active cognitive and behavioral coping was not related to the outcome measures.
本研究前瞻性地调查了181名男同性恋者中回避应对与积极认知及行为应对之间的关系，以及7年期间HIV感染的进展情况。研究结果显示，对于一些医学和行为因素，(a) 回避应对预示着CD4细胞下降率较低；(b) 避免产生合胞体诱导性HIV变体的比例风险（PH）为0.72（95%置信区间[CI]：0.53 - 0.99，p <.05）；(c) 避免CD4细胞降至低于200个/微升的PH为0.66（95%CI：0.50 - 0.89，p <.01）。回避应对与定义艾滋病的临床症状的发展无关。积极认知及行为应对与结局指标无关。
