Norcini Pala A, Steca P
HIV Center, 3rd Floor, Room 339, New York State Psychiatric Institute and College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, Unit 15, New York, NY, 10032, USA,
J Behav Med. 2015 Aug;38(4):620-31. doi: 10.1007/s10865-015-9639-0. Epub 2015 Apr 2.
Illness perceptions can influence the coping strategies used in response to HIV-related stressors, and ultimately patients' clinical status. With this work, we aimed to: (1) identify illness perception-related profiles of HIV-positive patients; (2) evaluate the association between the profiles, illness-related coping strategies, HIV-progression biomarkers (CD4+ cell counts and viral load) and antiretroviral therapy use. Data about illness perceptions, HIV-related coping strategies and HIV-progression biomarkers (CD4+ and viral load) were collected from 248 Italian HIV-positive patients. Three latent classes ("high," "moderate" and "low" influence perception) that differed on consequences, emotional representation, personal control and identity were identified. A greater perception of illness influence was associated with dysfunctional coping strategies (e.g., passive coping and alcohol use), and greater viral load was observed among patients with high and moderate influence perception. In conclusion, patients with detectable or high viral load may show a greater perception of illness influence (i.e., consequences), which is associated with dysfunctional coping strategies in response to HIV-related stressors.
疾病认知会影响应对与艾滋病病毒相关压力源时所采用的应对策略,最终影响患者的临床状况。通过这项研究,我们旨在:(1)识别艾滋病病毒阳性患者与疾病认知相关的特征;(2)评估这些特征、与疾病相关的应对策略、艾滋病病毒进展生物标志物(CD4+细胞计数和病毒载量)以及抗逆转录病毒疗法使用之间的关联。我们收集了248名意大利艾滋病病毒阳性患者关于疾病认知、与艾滋病病毒相关的应对策略以及艾滋病病毒进展生物标志物(CD4+和病毒载量)的数据。识别出了在后果、情感表征、个人控制和身份方面存在差异的三个潜在类别(“高”、“中”和“低影响认知”)。对疾病影响的更高认知与功能失调的应对策略(如消极应对和饮酒)相关,并且在高影响认知和中等影响认知的患者中观察到更高的病毒载量。总之,病毒载量可检测到或较高的患者可能对疾病影响(即后果)有更高的认知,这与应对与艾滋病病毒相关压力源时的功能失调应对策略有关。