Vogt P R, Hauser M, Schwarz U, Jenni R, Lachat M L, Zünd G, Schüpbach R W, Schmidlin D, Turina M I
Clinic for Cardiovascular Surgery, Institute for Diagnostic Radiology, Department of Neurology, University Hospital, Zurich, Switzerland.
Ann Thorac Surg. 1999 Feb;67(2):457-61. doi: 10.1016/s0003-4975(98)01239-9.
Arteriosclerotic plaques of the ascending aorta and transverse arch increase the operative risk of cardiac operations and are strong predictors for late cerebrovascular events.
Twenty-two patients, mean age 68 +/- 6 years (range, 55 to 77 years), with grade IV + V plaques of the ascending aorta and transverse arch underwent coronary artery bypass grafting (n = 21) and aortic valve replacement (n = 8). Cerebrovascular emboli from unknown sources were found preoperatively in 8 patients (36%). All were in sinus rhythm. Complete thromboendarterectomy of the ascending aorta and transverse arch was performed during hypothermic circulatory arrest. After 21 +/- 12 months (range, 4 to 44 months), magnetic resonance imaging and transthoracic echocardiography of endarterectomized vessels was performed.
There was one perioperative death (4.5%), one early (4.5%), and one late (4.7%) adverse neurologic event. Follow-up examinations revealed normal diameters of the endarterectomized aorta.
For patients with grade IV + V plaques, thromboendarterectomy of the ascending aorta and transverse arch can be performed with an acceptable surgical risk and a low recurrence rate for cerebrovascular events. Dilatation of the endarterectomized aorta was not observed.
升主动脉和主动脉弓的动脉粥样硬化斑块会增加心脏手术的手术风险,并且是晚期脑血管事件的有力预测指标。
22例平均年龄68±6岁(范围55至77岁)、升主动脉和主动脉弓有IV + V级斑块的患者接受了冠状动脉搭桥术(n = 21)和主动脉瓣置换术(n = 8)。术前在8例患者(36%)中发现了来源不明的脑血管栓子。所有患者均为窦性心律。在低温循环停止期间对升主动脉和主动脉弓进行了完整的血栓内膜切除术。在21±12个月(范围4至44个月)后,对接受内膜切除术的血管进行了磁共振成像和经胸超声心动图检查。
围手术期死亡1例(4.5%),早期不良神经事件1例(4.5%),晚期不良神经事件1例(4.7%)。随访检查显示接受内膜切除术的主动脉直径正常。
对于有IV + V级斑块的患者,升主动脉和主动脉弓血栓内膜切除术可在可接受的手术风险和较低的脑血管事件复发率下进行。未观察到接受内膜切除术的主动脉扩张。