Sudlow M, Thomson R, Kenny R A, Rodgers H
Department of Medicine, School of Clinical Medical Studies, University of Newcastle upon Tyne.
Br J Gen Pract. 1998 Nov;48(436):1775-8.
Anticoagulants are effective in preventing stroke in those with atrial fibrillation, but most patients remain untreated.
To investigate the prevalence of disability, cognitive impairment, and problems with compliance in a representative sample of the elderly with atrial fibrillation, and to determine whether they would want treatment and how they would like services to be arranged.
In a survey of a random sample of 4843 elderly subjects, those with atrial fibrillation were identified using electrocardiograms. Views on treatment were obtained using a structured interview. Disability was assessed using the Office of Population Censuses and Surveys Disability Scale and cognitive status using the Mini Mental State Examination. General practitioners were asked, via questionnaire, for their views on each subject's compliance.
Two hundred and seven elderly people with atrial fibrillation were identified. Almost all subjects expressed a willingness to undertake treatment to prevent stroke and preferred blood testing performed outside of hospital. Disability (82.7%), cognitive impairment (25.7%), and problems with compliance (25.0%) were common, but the prevalence of these difficulties was not substantially different from the general elderly population, and in many cases they could be overcome (e.g. only 10% of subjects had problems with compliance and no-one who could help them to comply).
Most elderly people with atrial fibrillation would accept treatment to prevent stroke. Disability, cognitive impairment, and problems with compliance may make it difficult to treat this patient group. An increase in the use of anticoagulants should be accompanied by the development of services appropriate to this frail population.
抗凝剂对预防房颤患者的中风有效,但大多数患者仍未接受治疗。
调查具有代表性的老年房颤患者样本中的残疾率、认知障碍及依从性问题,并确定他们是否愿意接受治疗以及希望如何安排服务。
在对4843名老年受试者的随机样本进行的调查中,通过心电图识别出房颤患者。使用结构化访谈获取对治疗的看法。使用人口普查和调查办公室残疾量表评估残疾情况,使用简易精神状态检查表评估认知状态。通过问卷调查向全科医生询问他们对每个受试者依从性的看法。
识别出207名老年房颤患者。几乎所有受试者都表示愿意接受预防中风的治疗,并且更倾向于在医院外进行血液检测。残疾(82.7%)、认知障碍(25.7%)和依从性问题(25.0%)很常见,但这些困难的发生率与一般老年人群没有实质性差异,并且在许多情况下可以克服(例如,只有10%的受试者存在依从性问题,且没有人能帮助他们依从)。
大多数老年房颤患者会接受预防中风的治疗。残疾、认知障碍和依从性问题可能使该患者群体的治疗变得困难。抗凝剂使用的增加应伴随着为这一脆弱人群开发适当的服务。