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Implantable stimulation system dedicated for neural selective stimulation.

作者信息

Robin S, Sawan M, Abdel-Gawad M, Abdel-Baky T M, Elhilali M M

机构信息

Department of Electrical and Computer Engineering, Ecole Polytechnique de Montréal, Canada.

出版信息

Med Biol Eng Comput. 1998 Jul;36(4):490-2. doi: 10.1007/BF02523220.

DOI:10.1007/BF02523220
PMID:10198535
Abstract

A functional electrical stimulation system is presented, which is dedicated for the selective neural stimulation of the bladder. The proposed system is composed of an internal stimulator (implant) and an external controller. The system is used to produce low-pressure voiding of the bladder in spinal cord injured patients. The implant is powered and operated by the external controller via radio-frequency electromagnetic coupling. All stimulation parameters are chosen externally using the controller and are sent to the implant, which produces the desired stimuli. These stimuli are applied directly to the S2 nerve which is linked to the sphincter and bladder muscles. A high-frequency signal is used to inhibit the contraction of the sphincter muscle, and low-frequency pulses stimulate the bladder muscle (the detrusor). Dedicated computer software is used by the physician to select the optimal parameters for each patient and to activate the implant through a parallel port interface with built-in transmitter. The parameters are then transferred to a hand-held controller which is used by the technical staff and by the patients themselves. Acute studies have been performed to validate the selective stimulation strategy, and chronic experimentation is currently underway in dogs.

摘要

相似文献

1
Implantable stimulation system dedicated for neural selective stimulation.
Med Biol Eng Comput. 1998 Jul;36(4):490-2. doi: 10.1007/BF02523220.
2
A new bladder stimulator--hand-held controller and miniaturized implant: preliminary results in dogs.一种新型膀胱刺激器——手持控制器和小型化植入物:犬类初步研究结果
Biomed Instrum Technol. 1993 Mar-Apr;27(2):143-9.
3
Bladder and urethral sphincter responses evoked by microstimulation of S2 sacral spinal cord in spinal cord intact and chronic spinal cord injured cats.脊髓完整和慢性脊髓损伤猫中,微刺激骶2脊髓所诱发的膀胱和尿道括约肌反应。
Exp Neurol. 2004 Nov;190(1):171-83. doi: 10.1016/j.expneurol.2004.07.001.
4
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5
Sacral root stimulation for controlled micturition: prevention of detrusor-external sphincter dyssynergia by intraoperative identification and selective section of sacral nerve branches.骶神经根刺激用于控制排尿:通过术中识别和选择性切断骶神经分支预防逼尿肌-外括约肌协同失调
J Urol. 1993 Jun;149(6):1607-12. doi: 10.1016/s0022-5347(17)36460-1.
6
Reduction of bladder outlet resistance by selective stimulation of the ventral sacral root using high frequency blockade: a chronic study in spinal cord transected dogs.使用高频阻滞选择性刺激骶前根降低膀胱出口阻力:脊髓横断犬的慢性研究
J Urol. 2001 Aug;166(2):728-33.
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Electrical nerve stimulation to promote micturition in spinal cord injury patients: A review of current attempts.电神经刺激促进脊髓损伤患者排尿:当前尝试的综述
Neurourol Urodyn. 2016 Mar;35(3):365-70. doi: 10.1002/nau.22730. Epub 2015 Feb 8.
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Neurol Res. 2002 Jul;24(5):413-30. doi: 10.1179/016164102101200294.
9
Treatment of neurogenic detrusor overactivity in spinal cord injured patients by conditional electrical stimulation.通过条件性电刺激治疗脊髓损伤患者的神经源性逼尿肌过度活动
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本文引用的文献

1
History of implantable devices.植入式设备的历史。
IEEE Eng Med Biol Mag. 1991;10(3):38-41. doi: 10.1109/51.84185.
2
Reduction of bladder outlet resistance by selective sacral root stimulation using high-frequency blockade in dogs: an acute study.犬高频阻滞选择性骶神经根刺激降低膀胱出口阻力的急性研究
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3
Selective detrusor activation by electrical sacral nerve root stimulation in spinal cord injury.脊髓损伤中通过电刺激骶神经根实现逼尿肌选择性激活。
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4
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Selective activation of small motor axons by quasi-trapezoidal current pulses.准梯形电流脉冲对小型运动轴突的选择性激活。
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