Ahmad H, Chapnick E K
Division of Infectious Diseases, Maimonides Medical Center, Brooklyn, New York, USA.
Infect Dis Clin North Am. 1999 Mar;13(1):113-33, vii. doi: 10.1016/s0891-5520(05)70046-5.
The joining of polysaccharide antigens to various proteins can result in increased immunogenicity of vaccines composed of such antigens. This article discusses conjugated polysaccharide vaccines for Haemophilus influenzae, Streptococcus pneumoniae, and Neisseria meningitis. Increased availability and use of such vaccines may result in the ability to give more effective vaccines earlier in life, further reducing the incidence of diseases caused by these organisms.
多糖抗原与各种蛋白质的结合可导致由此类抗原组成的疫苗免疫原性增强。本文讨论了针对流感嗜血杆菌、肺炎链球菌和脑膜炎奈瑟菌的结合多糖疫苗。此类疫苗可用性和使用的增加可能使人们有能力在生命早期接种更有效的疫苗，进一步降低由这些病原体引起的疾病的发病率。
