Van Hoogmoed L, Rodger L D, Spier S J, Gardner I A, Yarbrough T B, Snyder J R
Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis 95616, USA.
J Am Vet Med Assoc. 1999 Apr 1;214(7):1032-6.
To determine whether peritoneal fluid pH, glucose concentration, and lactate dehydrogenase activity can be used to differentiate horses with septic peritonitis from those with nonseptic peritonitis.
Prospective study.
46 horses, including 10 healthy horses, 15 horses with septic peritonitis, and 21 horses with nonseptic peritonitis.
Peritoneal fluid and blood samples were analyzed for pH, glucose concentration, and lactate dehydrogenase activity. Complete blood cell counts were performed, and peritoneal fluid samples were submitted for bacterial culture.
Horses with septic peritonitis had significantly lower peritoneal fluid pH and glucose concentrations than horses with nonseptic peritonitis and healthy horses. Compared with other tests, serum-to-peritoneal fluid glucose concentration differences > 50 mg/dl had the highest diagnostic use for detection of septic peritonitis. Peritoneal fluid pH < 7.3, glucose concentration < 30 mg/dl, and fibrinogen concentration > 200 mg/dl were also highly indicative of septic peritonitis.
Peritoneal fluid pH and glucose concentration can be used to assist in the identification of horses with septic peritonitis. These measurements can provide an early indication of sepsis, especially if cytologic evaluation of peritoneal fluid is unavailable or results are equivocal and peritoneal fluid bacterial culture results are pending.
确定腹腔液pH值、葡萄糖浓度和乳酸脱氢酶活性是否可用于区分患败血性腹膜炎的马和非败血性腹膜炎的马。
前瞻性研究。
46匹马，包括10匹健康马、15匹患败血性腹膜炎的马和21匹患非败血性腹膜炎的马。
分析腹腔液和血液样本的pH值、葡萄糖浓度和乳酸脱氢酶活性。进行全血细胞计数，并将腹腔液样本送去做细菌培养。
患败血性腹膜炎的马的腹腔液pH值和葡萄糖浓度显著低于患非败血性腹膜炎的马和健康马。与其他检测相比，血清与腹腔液葡萄糖浓度差值>50mg/dl对检测败血性腹膜炎的诊断用途最大。腹腔液pH值<7.3、葡萄糖浓度<30mg/dl和纤维蛋白原浓度>200mg/dl也高度提示败血性腹膜炎。
腹腔液pH值和葡萄糖浓度可用于辅助识别患败血性腹膜炎的马。这些测量值可提供败血症的早期迹象，特别是在无法进行腹腔液细胞学评估或结果不明确且腹腔液细菌培养结果待定的情况下。
