Abdo A, Bebb R A, Wilkins G E
Division of Endocrinology, St Paul's Hospital, University of British Columbia, Vancouver, Canada.
Can J Cardiol. 1999 Mar;15(3):347-8.
Patients with primary aldosteronism often present with hypokalemia and hypertension. Primary aldosteronism presenting as sudden death due to ventricular fibrillation is described in an otherwise healthy 37-year-old woman. After successful direct current cardioversion, serum potassium was 1.4 mmol/L. Investigations revealed a suppressed renin level, elevated serum aldosterone and a right adrenal nodule found on imaging. Ventricular fibrillation has not previously been described as a presention of a biochemically and surgically proven aldosterone-producing adenoma. This case highlights the importance of early detection and proper diagnosis of secondary hypertension before serious sequelae occur.
原发性醛固酮增多症患者常伴有低钾血症和高血压。本文描述了一名37岁身体健康的女性，因原发性醛固酮增多症导致心室颤动而猝死。成功进行直流电复律后，血清钾浓度为1.4 mmol/L。检查发现肾素水平降低、血清醛固酮升高，影像学检查发现右侧肾上腺有结节。此前尚未有将心室颤动描述为经生化和手术证实的醛固酮瘤表现的报道。该病例强调了在严重后遗症发生之前早期发现和正确诊断继发性高血压的重要性。
