Reinert R R, Conrads G, Schlaeger J J, Werner G, Witte W, Lütticken R, Klare I
National Reference Center for Streptococci, Institute of Medical Microbiology, University Hospital Aachen, D-52057 Aachen, Germany.
J Clin Microbiol. 1999 May;37(5):1638-41. doi: 10.1128/JCM.37.5.1638-1641.1999.
A surveillance study on antibiotic resistance of enterococcal isolates (n = 730) was carried out in North Rhine-Westphalia, Germany, in 1997. Resistance rates to ampicillin (7.4%), high-level gentamicin (15.0%), high-level streptomycin (27.9%), ciprofloxacin (37.9%), vancomycin (1.5%), and teicoplanin (1.5%) were determined. All vancomycin-resistant enterococci (VRE) carried the vanA gene. SmaI and ApaI macrorestriction patterns indicated an intra- and interhospital spread of VRE.
1997年,在德国北莱茵 - 威斯特法伦州开展了一项针对肠球菌分离株(n = 730)抗生素耐药性的监测研究。测定了对氨苄西林(7.4%)、高水平庆大霉素(15.0%)、高水平链霉素(27.9%)、环丙沙星(37.9%)、万古霉素(1.5%)和替考拉宁(1.5%)的耐药率。所有耐万古霉素肠球菌(VRE)均携带vanA基因。SmaI和ApaI酶切宏限制图谱表明VRE在医院内和医院间传播。