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[氟化钠治疗骨质疏松症的经验]

[Experiences with sodium fluoride in the treatment of osteoporosis].

作者信息

Geidel H

出版信息

Z Gesamte Inn Med. 1976 Dec 1;31(23):981-6.

PMID:1020401
Abstract

In 10 patients with primary and 13 patients with glucocorticoid osteoporosis a NaF-therapy with an average daily dose of 80 mg was carried out in a period of 1/2 to 4 1/2 years. 22 patients spoke about an improvement of the complaints. Radiologically an osteogenesis could be proved in 19 patients. Dose and duration of the therapy as well as eventual additional treatments, frequency and severity of the side-effects are discussed and the indication for a NaF-medication are elaborated.

摘要

对10例原发性骨质疏松患者和13例糖皮质激素性骨质疏松患者进行了为期半年至四年半的氟化钠治疗,平均每日剂量为80毫克。22例患者表示症状有所改善。放射学检查证实19例患者有骨生成。讨论了治疗的剂量、持续时间以及可能的额外治疗、副作用的频率和严重程度,并阐述了氟化钠用药的适应症。

相似文献

1
[Experiences with sodium fluoride in the treatment of osteoporosis].[氟化钠治疗骨质疏松症的经验]
Z Gesamte Inn Med. 1976 Dec 1;31(23):981-6.
2
[Treatment of osteoporosis with a delayed-action sodium fluoride preparation].[用缓释氟化钠制剂治疗骨质疏松症]
Z Rheumatol. 1977 Mar-Apr;36(3-4):126-39.
3
[Treatment of osteoporosis with a new retard-preparation of sodium fluoride (author's transl)].用新型缓释氟化钠制剂治疗骨质疏松症(作者译)
Wien Med Wochenschr. 1979 May 15;129(9):251-4.
4
[Results of long-term treatment of primary osteoporosis with sodium fluoride (author's transl)].氟化钠治疗原发性骨质疏松症的长期疗效(作者译)
Dtsch Med Wochenschr. 1978 Feb 10;103(6):248-52. doi: 10.1055/s-0028-1104416.
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[Effect of sodium fluoride on DNA metabolism during therapy for osteoporosis].[氟化钠在骨质疏松症治疗过程中对DNA代谢的影响]
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[Serum fluoride level in the NaF treatment of osteoporosis].[氟化钠治疗骨质疏松症时的血清氟水平]
Verh Dtsch Ges Inn Med. 1976;82 Pt 1:910-2.
7
Effect of fluoride therapy on nondialyzable urinary hydroxyproline, serum alkaline phosphatase, parathyroid hormone, and 25-hydroxyvitamin D.氟化物治疗对非透析性尿羟脯氨酸、血清碱性磷酸酶、甲状旁腺激素和25-羟维生素D的影响。
Metabolism. 1977 Sep;26(9):1005-10. doi: 10.1016/0026-0495(77)90018-x.
8
[Osteoporosis therapy and thyroid function. Influence of 6 months of sodium fluoride treatment on thyroid function and bone density].[骨质疏松症治疗与甲状腺功能。6个月氟化钠治疗对甲状腺功能和骨密度的影响]
Fortschr Med. 1981 Mar 12;99(10):342-8.
9
[Treatment of glucocorticoid osteoporosis using sodium fluoride].[使用氟化钠治疗糖皮质激素性骨质疏松症]
Dtsch Gesundheitsw. 1971 Dec 16;26(51):2398-402.
10
[Problems of high-dose sodium fluoride therapy in osteoporosis. 3. Practice of osteoporosis therapy with sodium fluoride].[骨质疏松症高剂量氟化钠疗法的问题。3. 氟化钠治疗骨质疏松症的实践]
Z Arztl Fortbild (Jena). 1979 Jun 15;73(12):581-4.