Siech M, Tripp K, Schmidt-Rohlfing B, Mattfeldt T, Görich J, Beger H G
Department of General Surgery, University of Ulm, Germany.
Am J Surg. 1999 Feb;177(2):117-20. doi: 10.1016/s0002-9610(98)00315-8.
Since 1996 the classification of pancreatic tumors was replaced by the new World Health Organization nomenclature. Formerly mucinous cystadenomas are now distinguished between intraductal papillary mucinous tumors of the pancreas (IPMT) and mucinous cystadenomas.
We reevaluated the pathological specimen and surgical therapy of 23 consecutive patients and followed up these patients up for 4 years in median. Between 1987 and 1997 we treated 8 patients with IPMT and 15 patients with mucinous cystadenomas.
Eighty-five per cent of all patients were symptomatic. Ultrasonography and computed tomography were the most sensitive diagnostic techniques. In 25%, the entire pancreas was involved with IPMT; that was not the case in any of the patients with mucinous cystadenoma. All patients were resected with no perioperative mortality. After dismissal from the hospital, all resected patients are still alive after a median follow-up of 4 years. In no patient with IPMT, but in 1 patient with mucinous cystadenoma, the tumor recurred.
Surgical resection is the treatment of choice in all cystic tumors, and the late outcome of IPMT is as good as for mucinous cystadenoma.
自1996年起,胰腺肿瘤的分类被世界卫生组织的新命名法所取代。以前的黏液性囊腺瘤现在被区分为胰腺导管内乳头状黏液性肿瘤(IPMT)和黏液性囊腺瘤。
我们重新评估了连续23例患者的病理标本和手术治疗情况,并对这些患者进行了中位时间为4年的随访。在1987年至1997年期间,我们治疗了8例IPMT患者和15例黏液性囊腺瘤患者。
所有患者中有85%出现症状。超声检查和计算机断层扫描是最敏感的诊断技术。25%的IPMT患者整个胰腺受累;黏液性囊腺瘤患者中无一例出现这种情况。所有患者均接受了手术切除,无围手术期死亡。出院后,所有接受手术切除的患者在中位随访4年后仍存活。IPMT患者中无一例肿瘤复发,但1例黏液性囊腺瘤患者出现肿瘤复发。
手术切除是所有囊性肿瘤的首选治疗方法,IPMT的远期疗效与黏液性囊腺瘤相同。