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本文引用的文献

1
Immunoglobulin class switch recombination: will genetics provide new clues to mechanism?免疫球蛋白类别转换重组：遗传学能否为其机制提供新线索？
Am J Hum Genet. 1999 May;64(5):1270-5. doi: 10.1086/302393.
2
Characterization of cell cycle checkpoint responses after ionizing radiation in Nijmegen breakage syndrome cells.奈梅亨断裂综合征细胞经电离辐射后细胞周期检查点反应的特征分析。
Cancer Res. 1998 Jun 1;58(11):2316-22.
3
The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response.人源Mre11/hRad50蛋白复合体与尼曼匹克氏症候群：双链断裂修复与细胞DNA损伤反应的关联
Cell. 1998 May 1;93(3):477-86. doi: 10.1016/s0092-8674(00)81175-7.
4
Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome.尼布林是一种新型的DNA双链断裂修复蛋白，在尼曼-匹克氏病C型综合征中发生突变。
Cell. 1998 May 1;93(3):467-76. doi: 10.1016/s0092-8674(00)81174-5.
5
In situ visualization of DNA double-strand break repair in human fibroblasts.人成纤维细胞中DNA双链断裂修复的原位可视化
Science. 1998 Apr 24;280(5363):590-2. doi: 10.1126/science.280.5363.590.
6
Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart.共济失调毛细血管扩张症与奈梅亨断裂综合征：相关疾病但基因不同。
Annu Rev Genet. 1997;31:635-62. doi: 10.1146/annurev.genet.31.1.635.
7
hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks.在正常细胞对DNA双链断裂的反应过程中，hMre11和hRad50核灶被诱导产生。
Mol Cell Biol. 1997 Oct;17(10):6087-96. doi: 10.1128/MCB.17.10.6087.
8
Nijmegen breakage syndrome cells fail to induce the p53-mediated DNA damage response following exposure to ionizing radiation.奈梅亨断裂综合征细胞在暴露于电离辐射后无法诱导p53介导的DNA损伤反应。
Mol Cell Biol. 1997 Sep;17(9):5016-22. doi: 10.1128/MCB.17.9.5016.
9
Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells.通过Cre重组酶进行的条件性基因靶向缺失证明了小鼠胚胎干细胞中双链断裂修复蛋白Mre11的必要性。
Nucleic Acids Res. 1997 Aug 1;25(15):2985-91. doi: 10.1093/nar/25.15.2985.
10
The RAD52 epistasis group in mammalian double strand break repair.哺乳动物双链断裂修复中的RAD52上位性基因群。
Semin Immunol. 1997 Jun;9(3):181-8. doi: 10.1006/smim.1997.0067.

The mammalian Mre11-Rad50-nbs1 protein complex: integration of functions in the cellular DNA-damage response.

作者信息

Petrini J H

机构信息

Laboratory of Genetics, University of Wisconsin Medical School, Madison, WI 53706, USA.

出版信息

Am J Hum Genet. 1999 May;64(5):1264-9. doi: 10.1086/302391.

DOI:10.1086/302391
PMID:10205255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1377860/
Abstract
摘要