The mammalian Mre11-Rad50-nbs1 protein complex: integration of functions in the cellular DNA-damage response.
作者信息
Petrini J H
机构信息
Laboratory of Genetics, University of Wisconsin Medical School, Madison, WI 53706, USA.
出版信息
Am J Hum Genet. 1999 May;64(5):1264-9. doi: 10.1086/302391.
Abstract
摘要
相似文献
1
The mammalian Mre11-Rad50-nbs1 protein complex: integration of functions in the cellular DNA-damage response.哺乳动物的Mre11-Rad50-nbs1蛋白复合物：细胞DNA损伤应答中功能的整合
Am J Hum Genet. 1999 May;64(5):1264-9. doi: 10.1086/302391.
2
Intracellular redistribution and modification of proteins of the Mre11/Rad50/Nbs1 DNA repair complex following irradiation and heat-shock.辐照和热休克后Mre11/Rad50/Nbs1 DNA修复复合物蛋白质的细胞内重新分布及修饰
J Cell Physiol. 2004 May;199(2):157-70. doi: 10.1002/jcp.10475.
3
The Mre11 complex and the metabolism of chromosome breaks: the importance of communicating and holding things together.Mre11复合物与染色体断裂的代谢：沟通与维系的重要性
DNA Repair (Amst). 2004 Aug-Sep;3(8-9):845-54. doi: 10.1016/j.dnarep.2004.03.014.
4
[The gene for Nijmegen breakage syndrome and its function in rejoining double-strand break].[尼曼-匹克氏病C型基因及其在双链断裂修复中的作用]
Tanpakushitsu Kakusan Koso. 2001 Jun;46(8 Suppl):1038-45.
5
Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair.设想Mre11-Rad50-Nbs1复合物的动力学和灵活性，以解读其在DNA复制和修复中的作用。
Prog Biophys Mol Biol. 2015 Mar;117(2-3):182-193. doi: 10.1016/j.pbiomolbio.2014.12.004. Epub 2015 Jan 7.
6
MRE11/RAD50/NBS1: complex activities.MRE11/RAD50/NBS1：复合活性
Chromosoma. 2004 Oct;113(4):157-66. doi: 10.1007/s00412-004-0306-4. Epub 2004 Aug 10.
7
Nbs1 moving up in the world.Nbs1在行业中地位上升。
Nat Cell Biol. 2005 Jul;7(7):648-50. doi: 10.1038/ncb0705-648.
8
Arginine methylation of MRE11 by PRMT1 is required for DNA damage checkpoint control.PRMT1对MRE11进行精氨酸甲基化是DNA损伤检查点控制所必需的。
Genes Dev. 2005 Mar 15;19(6):671-6. doi: 10.1101/gad.1279805. Epub 2005 Mar 1.
9
A murine model of Nijmegen breakage syndrome.奈梅亨断裂综合征的小鼠模型。
Curr Biol. 2002 Apr 16;12(8):648-53. doi: 10.1016/s0960-9822(02)00763-7.
10
The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response.人源Mre11/hRad50蛋白复合体与尼曼匹克氏症候群：双链断裂修复与细胞DNA损伤反应的关联
Cell. 1998 May 1;93(3):477-86. doi: 10.1016/s0092-8674(00)81175-7.
引用本文的文献
1
LINC00467 mediates the 5-fluorouracil resistance in breast cancer cells.LINC00467 介导乳腺癌细胞对 5-氟尿嘧啶的耐药性。
In Vitro Cell Dev Biol Anim. 2024 Jan;60(1):80-88. doi: 10.1007/s11626-023-00832-9. Epub 2023 Dec 21.
2
Ionizing Radiation Protein Biomarkers in Normal Tissue and Their Correlation to Radiosensitivity: A Systematic Review.正常组织中的电离辐射蛋白质生物标志物及其与放射敏感性的相关性：一项系统综述。
J Pers Med. 2021 Feb 19;11(2):140. doi: 10.3390/jpm11020140.
3
Ionizing Radiation Protein Biomarkers in Normal Tissue and Their Correlation to Radiosensitivity: Protocol for a Systematic Review.正常组织中的电离辐射蛋白质生物标志物及其与放射敏感性的相关性：系统评价方案
J Pers Med. 2020 Dec 22;11(1):3. doi: 10.3390/jpm11010003.
4
EGFR Mutations Compromise Hypoxia-Associated Radiation Resistance through Impaired Replication Fork-Associated DNA Damage Repair.EGFR 突变通过损害复制叉相关的 DNA 损伤修复来影响与缺氧相关的辐射抗性。
Mol Cancer Res. 2017 Nov;15(11):1503-1516. doi: 10.1158/1541-7786.MCR-17-0136. Epub 2017 Aug 11.
5
Biological determinants of radioresistance and their remediation in pancreatic cancer.胰腺癌放射抵抗的生物学决定因素及其逆转。
Biochim Biophys Acta Rev Cancer. 2017 Aug;1868(1):69-92. doi: 10.1016/j.bbcan.2017.02.003. Epub 2017 Feb 27.
6
Association of Human Papillomavirus 16 E2 with Rad50-Interacting Protein 1 Enhances Viral DNA Replication.人乳头瘤病毒16 E2与Rad50相互作用蛋白1的关联增强病毒DNA复制。
J Virol. 2017 Feb 14;91(5). doi: 10.1128/JVI.02305-16. Print 2017 Mar 1.
7
Functional Analysis of the Bacteriophage T4 Rad50 Homolog (gp46) Coiled-coil Domain.噬菌体T4 Rad50同源物（gp46）卷曲螺旋结构域的功能分析
J Biol Chem. 2015 Sep 25;290(39):23905-15. doi: 10.1074/jbc.M115.675132. Epub 2015 Aug 4.
8
Identification of Plasmodium falciparum DNA Repair Protein Mre11 with an Evolutionarily Conserved Nuclease Function.恶性疟原虫DNA修复蛋白Mre11的鉴定及其具有进化保守核酸酶功能的研究
PLoS One. 2015 May 4;10(5):e0125358. doi: 10.1371/journal.pone.0125358. eCollection 2015.
9
T-oligo as an anticancer agent in colorectal cancer.T-寡核苷酸作为结直肠癌的抗癌剂。
Biochem Biophys Res Commun. 2014 Apr 4;446(2):596-601. doi: 10.1016/j.bbrc.2014.03.013. Epub 2014 Mar 12.
10
The timing of neural stem cell-based virotherapy is critical for optimal therapeutic efficacy when applied with radiation and chemotherapy for the treatment of glioblastoma.神经干细胞病毒疗法的时机对于胶质母细胞瘤的放化疗联合应用的最佳治疗效果至关重要。
Stem Cells Transl Med. 2013 Sep;2(9):655-66. doi: 10.5966/sctm.2013-0039. Epub 2013 Aug 7.
本文引用的文献
1
Immunoglobulin class switch recombination: will genetics provide new clues to mechanism?免疫球蛋白类别转换重组：遗传学能否为其机制提供新线索？
Am J Hum Genet. 1999 May;64(5):1270-5. doi: 10.1086/302393.
2
Characterization of cell cycle checkpoint responses after ionizing radiation in Nijmegen breakage syndrome cells.奈梅亨断裂综合征细胞经电离辐射后细胞周期检查点反应的特征分析。
Cancer Res. 1998 Jun 1;58(11):2316-22.
3
The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response.人源Mre11/hRad50蛋白复合体与尼曼匹克氏症候群：双链断裂修复与细胞DNA损伤反应的关联
Cell. 1998 May 1;93(3):477-86. doi: 10.1016/s0092-8674(00)81175-7.
4
Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome.尼布林是一种新型的DNA双链断裂修复蛋白，在尼曼-匹克氏病C型综合征中发生突变。
Cell. 1998 May 1;93(3):467-76. doi: 10.1016/s0092-8674(00)81174-5.
5
In situ visualization of DNA double-strand break repair in human fibroblasts.人成纤维细胞中DNA双链断裂修复的原位可视化
Science. 1998 Apr 24;280(5363):590-2. doi: 10.1126/science.280.5363.590.
6
Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart.共济失调毛细血管扩张症与奈梅亨断裂综合征：相关疾病但基因不同。
Annu Rev Genet. 1997;31:635-62. doi: 10.1146/annurev.genet.31.1.635.
7
hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks.在正常细胞对DNA双链断裂的反应过程中，hMre11和hRad50核灶被诱导产生。
Mol Cell Biol. 1997 Oct;17(10):6087-96. doi: 10.1128/MCB.17.10.6087.
8
Nijmegen breakage syndrome cells fail to induce the p53-mediated DNA damage response following exposure to ionizing radiation.奈梅亨断裂综合征细胞在暴露于电离辐射后无法诱导p53介导的DNA损伤反应。
Mol Cell Biol. 1997 Sep;17(9):5016-22. doi: 10.1128/MCB.17.9.5016.
9
Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells.通过Cre重组酶进行的条件性基因靶向缺失证明了小鼠胚胎干细胞中双链断裂修复蛋白Mre11的必要性。
Nucleic Acids Res. 1997 Aug 1;25(15):2985-91. doi: 10.1093/nar/25.15.2985.
10
The RAD52 epistasis group in mammalian double strand break repair.哺乳动物双链断裂修复中的RAD52上位性基因群。
Semin Immunol. 1997 Jun;9(3):181-8. doi: 10.1006/smim.1997.0067.
Zotero 插件