Fischer U, Hommel H, Nowak W, Sill U, Lippert H
Acta Biol Med Ger. 1976;35(10):1293-300.
During an intravenous glucose test, conscious dogs with exocrine pancreatic fistulas showed a reduction in the secretions of water, protein and of bicarbonate. This reduction is related to hyperglycemia and to IRI increase in the peripheral venous blood. After oral administration of glucose, however, a biphasic stimulation of the exocrine function was observed. During the first 15 minutes when insulin secretion increases independently of the blood glucose increase, all exocrine pancreatic functions are transiently stimulated, too. A second peak of the exocrine secretions is to be observed when glucose absorption and insulin secretion exhibit their maximum.
在静脉葡萄糖试验期间，患有外分泌性胰瘘的清醒犬的水、蛋白质和碳酸氢盐分泌减少。这种减少与外周静脉血中的高血糖和IRI增加有关。然而，口服葡萄糖后，观察到外分泌功能的双相刺激。在最初的15分钟内，当胰岛素分泌独立于血糖升高而增加时，所有胰腺外分泌功能也会受到短暂刺激。当葡萄糖吸收和胰岛素分泌达到最大值时，可观察到外分泌的第二个峰值。
