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口服葡萄糖后清醒犬的胰腺血流情况

Pancreatic blood flow in conscious dogs after oral administration of glucose.

作者信息

Fischer U, Hommel H, Salzsieder E

出版信息

Diabetologia. 1976 May;12(2):133-6. doi: 10.1007/BF00428978.

DOI:10.1007/BF00428978
PMID:1269846
Abstract

Dogs with electromagnetic flowprobe implanted around the superior pancreaticoduodenal artery and with an hydraulic occluder implanted upstream from the flowprobe were examined between the 3rd and the 8th postoperative day. During an oral glucose load, blood flow increased from the beginning of administration to about 25 minutes, but not when blood glucose and plasma IRI exhibit their maxima. The rise of pancreatic blood flow is assumed to be produced by reflexes similar to those stimulating insulin secretion and exocrine pancreatic function during the early phase of an oral glucose load.

摘要

在术后第3天至第8天期间,对在胰十二指肠上动脉周围植入电磁血流探头并在血流探头上游植入液压阻塞器的犬进行了检查。在口服葡萄糖负荷期间,从给药开始到约25分钟时血流增加,但在血糖和血浆胰岛素释放免疫反应性达到最大值时血流并未增加。胰腺血流的增加被认为是由类似于在口服葡萄糖负荷早期刺激胰岛素分泌和胰腺外分泌功能的反射所产生的。

相似文献

1
Pancreatic blood flow in conscious dogs after oral administration of glucose.口服葡萄糖后清醒犬的胰腺血流情况
Diabetologia. 1976 May;12(2):133-6. doi: 10.1007/BF00428978.
2
The mechanism of insulin secretion after oral glucose administration. VII. Exocrine pancreatic function and plasma-IRI in dogs with chronic pancreatic fistulas.口服葡萄糖后胰岛素分泌的机制。VII. 慢性胰瘘犬的胰腺外分泌功能与血浆胰岛素免疫反应性
Acta Biol Med Ger. 1976;35(10):1293-300.
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引用本文的文献

1
Pancreatic blood flow in hemorrhagic shock.失血性休克时的胰腺血流
Pflugers Arch. 1980 Aug;386(3):277-80. doi: 10.1007/BF00587479.
2
Stimulation by glucose of the blood flow to the pancreatic islets of the rat.葡萄糖对大鼠胰岛血流的刺激作用。
Diabetologia. 1983 Jul;25(1):45-50. doi: 10.1007/BF00251896.
3
Hypovolemic shock, pancreatic blood flow, and pancreatitis.
Int J Pancreatol. 1988 May;3(4):283-92. doi: 10.1007/BF02788457.

本文引用的文献

1
Some observations on changes in the blood content of the cat's pancreas during activity.关于猫胰腺在活动期间血液含量变化的一些观察
J Physiol. 1960 Mar;150(3):479-88. doi: 10.1113/jphysiol.1960.sp006399.
2
Changes in peripheral blood flow distribution in healthy dogs.健康犬外周血流分布的变化。
Circ Res. 1961 May;9:675-87. doi: 10.1161/01.res.9.3.675.
3
Effect of digestion on distribution of blood flow in the rat.
Science. 1957 Dec 6;126(3284):1176. doi: 10.1126/science.126.3284.1176.
4
Duplication of the blood glucose curve of an OGTT in dogs by a prospectively programmed I.V. infusion: infusion pattern and IRI response.通过前瞻性编程的静脉输注复制犬口服葡萄糖耐量试验的血糖曲线:输注模式和胰岛素反应。
Acta Diabetol Lat. 1978 Sep-Dec;15(5-6):294-302. doi: 10.1007/BF02590753.
4
The relation between pancreatic secretion and local blood flow: a review.胰腺分泌与局部血流的关系:综述
Gastroenterology. 1957 Apr;32(4):633-41.
5
Influence of hormones and drugs on canine pancreatic blood flow.激素和药物对犬胰腺血流的影响。
Am J Physiol. 1966 Dec;211(6):1398-402. doi: 10.1152/ajplegacy.1966.211.6.1398.
6
The effect of glucose and insulin on pancreatic blood flow in the anesthetized pig.葡萄糖和胰岛素对麻醉猪胰腺血流的影响。
Scand J Clin Lab Invest. 1971 Apr;27(2):105-11. doi: 10.3109/00365517109080195.
7
The secretion of pancreatic juice in response to stimulation of the vagus nerves in the pig.猪迷走神经受刺激时胰液的分泌
J Physiol. 1970 Feb;206(2):275-97. doi: 10.1113/jphysiol.1970.sp009013.
8
[Canine pancreatic regulation of insulin secretion in situ].[犬原位胰腺对胰岛素分泌的调节]
Journ Annu Diabetol Hotel Dieu. 1969;10:139-55.
9
Pancreatic blood flow and its relationship to insulin secretion during extracorporeal circulation.体外循环期间的胰腺血流及其与胰岛素分泌的关系。
Ann Surg. 1969 Nov;170(5):753-8. doi: 10.1097/00000658-196911000-00006.
10
The mechanism of insulin secretion after oral glucose administration. I. Multiphasic course of insulin mobilization after oral administration of glucose in conscious dogs. Differences to the behaviour after intravenous administration.口服葡萄糖后胰岛素分泌的机制。I. 清醒犬口服葡萄糖后胰岛素动员的多相过程。与静脉注射后行为的差异。
Diabetologia. 1972 Apr;8(2):104-10. doi: 10.1007/BF01235634.