Szeri I, Csóka R
Acta Microbiol Acad Sci Hung. 1976;23(3):235-7.
Acute toxoplasmosis was induced in CFLP mice by infecting them intraperitoneally with the 25 x 10(3) multiplicity of the virulent RH strain of Toxoplasma gondii. The lymphoid system of mice succumbing to acute toxoplasmosis showed characteristic changes. Significant spleen hypertrophy (spleen index: 1.76), severe thymus atrophy (thymus index: 0.27) and a striking decrease of the lymphocyte count in blood (86%) was found as compared with the uninfected controls.
通过向CFLP小鼠腹腔注射25×10³毒力强的刚地弓形虫RH株，诱导其发生急性弓形虫病。死于急性弓形虫病的小鼠淋巴系统呈现出特征性变化。与未感染的对照组相比，发现脾脏显著肥大（脾脏指数：1.76）、胸腺严重萎缩（胸腺指数：0.27）以及血液中淋巴细胞计数显著下降（86%）。
