Eisner M D, Gordon R L, Webb W R, Gold W M, Hilal S E, Edinburgh K, Golden J A
Department of Medicine, Cardiovascular Research Institute, University of California, San Francisco 94143-0924, USA.
Chest. 1999 Apr;115(4):1006-11. doi: 10.1378/chest.115.4.1006.
To determine whether expandable metal stent placement for benign airway lesions improves pulmonary function.
Case series.
University medical center.
Nine patients who underwent balloon-mediated expandable metal stent deployment for airway obstruction due to benign etiologies.
All nine patients had expandable stents deployed for benign airway lesions using fiberoptic bronchoscopy and fluoroscopic guidance. Pulmonary function improved after stent placement. The mean FVC increased by 388 mL (95% confidence interval [CI], 30 to 740 mL), the mean peak expiratory flow (PEF) increased by 1,288 mL (95% CI, 730 to 1,840 mL), the mean FEV1 increased by 550 mL (95% CI, 240 to 860 mL), and the mean forced expiratory flow between 25% and 50% of vital capacity (FEF25-75%) increased by 600 mL (95% CI, 110 to 1,090 mL). Corresponding relative measurements included increases in FVC (12%), PEF (95%), FEV1 (38%), and FEF25-75% (87%). The complete characterization of a benign airway obstruction generally required a multimodal approach.
Expandable metal stent placement appears to be an effective therapy for benign airway obstruction.
确定用于良性气道病变的可扩张金属支架置入术是否能改善肺功能。
病例系列研究。
大学医学中心。
9例因良性病因导致气道阻塞而接受球囊介导的可扩张金属支架置入术的患者。
所有9例患者均在纤维支气管镜和透视引导下为良性气道病变置入了可扩张支架。支架置入后肺功能得到改善。平均用力肺活量（FVC）增加了388毫升（95%置信区间[CI]，30至740毫升），平均呼气峰值流速（PEF）增加了1288毫升（95%CI，730至1840毫升），平均第1秒用力呼气容积（FEV1）增加了550毫升（95%CI，240至860毫升），平均肺活量25%至50%之间的用力呼气流量（FEF25 - 75%）增加了600毫升（95%CI，110至1090毫升）。相应的相对测量值包括FVC增加12%、PEF增加95%、FEV1增加38%以及FEF25 - 75%增加87%。对良性气道阻塞的完整特征描述通常需要多模式方法。
可扩张金属支架置入术似乎是治疗良性气道阻塞的有效方法。
