Suppr超能文献

上气道哮鸣:可诱导性喉梗阻与过度动态气道塌陷

Upper airway wheezing: Inducible laryngeal obstruction vs. excessive dynamic airway collapse.

作者信息

Rendo Matthew, Sjulin Tyson J, Morris Michael J, Burguete Sergio

机构信息

San Antonio Military Medical Center, Internal Medicine, 3551 Roger Brooke Drive, Fort Sam Houston, TX, 78234-6160, USA.

San Antonio Military Medical Center, Pulmonary/Critical Care, USA.

出版信息

Respir Med Case Rep. 2019 Mar 28;27:100827. doi: 10.1016/j.rmcr.2019.100827. eCollection 2019.

Abstract

There are multiple causes of dyspnea upon exertion in young, healthy patients to primarily include asthma and exercise-induced bronchospasm. (EDAC) describes focal collapse of the trachea or main bronchi with maintained structural integrity of the cartilaginous rings. It is commonly associated with pulmonary disorders like bronchiectasis, chronic obstructive pulmonary disease and asthma. It is believed to result secondary to airway obstruction in these conditions. While uncommon in young, healthy adults, it has recently been found as a cause of dyspnea in this population. Inducible laryngeal obstruction (ILO) is an umbrella term that describes an induced, intermittent upper airway impediment. While ILO is found in 10% of young patients with exertional dyspnea, it is primarily inspiratory in nature due to paradoxical closure of the glottis or supraglottis. This report highlights the presentation of a United States Army soldier who after a deployment was given a diagnosis of asthma, later found to have ILO and was subsequently diagnosed with concurrent EDAC. We follow up with a literature review and discussion of symptomatology, diagnosis, exercise bronchoscopy, and treatment modalities for both EDAC and ILO.

摘要

在年轻健康的患者中,运动性呼吸困难有多种原因,主要包括哮喘和运动诱发的支气管痉挛。气管软化(EDAC)描述的是气管或主支气管的局灶性塌陷,而软骨环的结构完整性得以保留。它通常与支气管扩张、慢性阻塞性肺疾病和哮喘等肺部疾病相关。据信,在这些情况下,它是由气道阻塞继发引起的。虽然在年轻健康的成年人中并不常见,但最近在这一人群中发现它是运动性呼吸困难的一个原因。可诱导性喉梗阻(ILO)是一个概括性术语,描述的是一种诱发的、间歇性的上气道梗阻。虽然在10%的运动性呼吸困难的年轻患者中发现有ILO,但由于声门或声门上的反常关闭,其本质上主要是吸气性的。本报告重点介绍了一名美国陆军士兵的情况,他在部署后被诊断为哮喘,后来发现患有ILO,随后被诊断为同时患有EDAC。我们通过文献综述以及对EDAC和ILO的症状学、诊断、运动支气管镜检查和治疗方式进行讨论来跟进。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bfa2/6446124/11a13e146810/gr1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验