D'Addazio G, Scordamaglia R, Tedeschi U, Barra M, Arpe F, Beatini L, Meola V
III Divisione Chirurgia Generale, Ospedale Regionale S. Martino, Genova.
Minerva Chir. 1998 Dec;53(12):1001-7.
The emergency surgical treatment of inflammatory chronic bowel diseases is closely related to the classification of patients according to their symptoms and clinical conditions, as well as possible surgical options. In our study, an actual set of criteria is proposed for the classification of the degree of seriousness of symptoms, related to patient conditions, and applicable surgical strategies.
Retrospectively evaluation of the outcome of the disease has been performed over 26 patients undergoing emergency treatment in our Hospital, and with at least 5 years of follow-up. Fourteen patients were affected by ulcerative rectocolitis and 11 underwent subtotal colectomy with ileostomy; the remaining 12 were affected by Crohn's disease and were treated with colic or ileal local resection.
Among 11 operated patients with RCU, 6 toxic megacolon, 4 severe colitis and one perforation (postoperative death) have been diagnosed. Recanalization was possible in 8 patients. On the other hand proctectomy was necessary in the remaining 3 patients as final operation. In MC patients 6 occlusions, 4 severe colitis, one multiple perineal fistulization and one perforation of occult right colon tumor have been diagnosed. We performed 5 right colectomy, 4 jejuno-ileal resections, one Hartmann's operation, one colostomy in emergency and one multiple bypass. Because of recurrence, one right colectomy needed following total colectomy and two jejuno-ileal resections needed right colectomy soon after. Three jejuno-ileal resections were performed with a conservative purpose in patients treated by right colectomy.
It has resulted that in ulcerative rectocolitis total colectomy actually permits an adequate control of the disease, as well as a satisfactory therapy of the rectal stump, with subsequent recanalization in the majority of cases, whereas in Crohn's disease the frequency of recidive is higher and it seems more advisable to opt for a radical resection treatment (chiefly right colectomy), but with a conservative purpose.
炎症性慢性肠病的急诊手术治疗与根据患者症状和临床状况进行的分类以及可能的手术选择密切相关。在我们的研究中,提出了一套实际的标准,用于对与患者状况相关的症状严重程度进行分类以及适用的手术策略。
对我院26例接受急诊治疗且至少随访5年的患者的疾病转归进行了回顾性评估。14例患者患有溃疡性直肠结肠炎,11例行次全结肠切除术并回肠造口术;其余12例患有克罗恩病,接受结肠或回肠局部切除术治疗。
在11例接受手术的溃疡性直肠结肠炎患者中,诊断出6例中毒性巨结肠、4例重症结肠炎和1例穿孔(术后死亡)。8例患者实现了再通。另一方面,其余3例患者最终需要行直肠切除术。在患有中毒性巨结肠的患者中,诊断出6例肠梗阻、4例重症结肠炎、1例多发性会阴瘘和1例隐匿性右结肠肿瘤穿孔。我们进行了5例右半结肠切除术、4例空肠回肠切除术、1例哈特曼手术、1例急诊结肠造口术和1例多处旁路手术。由于复发,1例右半结肠切除术后需要行全结肠切除术,2例空肠回肠切除术后不久需要行右半结肠切除术。在接受右半结肠切除术治疗的患者中,为了保守目的进行了3例空肠回肠切除术。
结果表明,在溃疡性直肠结肠炎中,全结肠切除术实际上能够充分控制疾病,并对直肠残端进行令人满意的治疗,大多数情况下随后可实现再通,而在克罗恩病中,复发频率较高,似乎更宜选择根治性切除治疗(主要是右半结肠切除术),但目的是保守性的。