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[溃疡性直肠结肠炎和结肠克罗恩病的急诊外科治疗]

[Emergency surgical treatment of ulcerative rectocolitis and Crohn's disease of the colon].

作者信息

Ginanneschi U, Fabiani P, Rizzi M, Fanti G

机构信息

Istituto di Chirurgia Generale, Università degli Studi di Trieste.

出版信息

Ann Ital Chir. 1996 Mar-Apr;67(2):193-6.

PMID:8929034
Abstract

We examine the indications and the operative options for proceeding to emergency surgery in patients with inflammatory bowel disease. Emergency surgery is absolutely mandatory in case of generalized peritonitis due to bowel perforation. Other life-treating complications are acute disease not responding to medical treatment, toxic megacolon, bowel obstruction and massive hemorrhage. Early medical treatment of these conditions often prevents most severe clinical expressions and improves the prognosis. However surgery should be performed immediately if there is no improvement within 5 days of medical management in case of acute colitis, within 24-48 hours in case of toxic megacolon, within 48-72 hours in patients with intestinal obstruction or severe bleeding, or if the patient deteriorates during this period. In such circumstances, subtotal colectomy with ileostomy and mucous fistula of distal sigmoid colon is the best procedure. That is because it is relatively easy to perform and consents a simpler restorative operation than other procedures preserving the rectum. Moreover it leads to lower morbidity and mortality than the total proctocolectomy that should be reserved to patients with severe rectal disease or sphincter lesion. The most important factors influencing outcome of complicated or severe inflammatory bowel disease are the choice of the appropriate timing for surgery and the procedure performed.

摘要

我们研究了炎症性肠病患者进行急诊手术的适应症和手术选择。因肠穿孔导致弥漫性腹膜炎时,急诊手术绝对必要。其他危及生命的并发症包括对药物治疗无反应的急性疾病、中毒性巨结肠、肠梗阻和大量出血。对这些情况进行早期药物治疗通常可预防最严重的临床表现并改善预后。然而,如果在药物治疗后,急性结肠炎患者5天内无改善、中毒性巨结肠患者24 - 48小时内无改善、肠梗阻或严重出血患者48 - 72小时内无改善,或者在此期间患者病情恶化,则应立即进行手术。在这种情况下,次全结肠切除术加回肠造口术和乙状结肠远端黏液瘘是最佳手术方式。这是因为该手术相对容易实施,且与保留直肠的其他手术相比,恢复性手术更简单。此外,与应保留给患有严重直肠疾病或括约肌病变患者的全直肠结肠切除术相比,它导致的发病率和死亡率更低。影响复杂或严重炎症性肠病预后的最重要因素是手术时机的选择和所实施的手术方式。

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