Silliman R A, Lash T L
Boston University School of Medicine, Boston-Medical Center, MA 02118, USA.
Med Care. 1999 Apr;37(4):339-49. doi: 10.1097/00005650-199904000-00004.
To compare patient interview-based and medical-record based measures of comorbidity and their relation to primary tumor therapy, all cause mortality, self-reported upper body function, and overall physical function.
Three-hundred and three breast cancer patients (> or = 55 years) who were diagnosed in 1 of 5 Boston hospitals were enrolled. Patient interviews and medical record abstracts provided the information necessary to construct the Charlson index, Satariano index, and a new interview-based index of cardiopulmonary comorbidity. Those indices were used alone and in combination to predict the patient outcomes.
The indices of comorbidity corresponded well with one another. No index of comorbidity predicted mortality or receipt of definitive primary therapy. The new interview-based index of cardiopulmonary comorbidity was a better predictor of upper body function and overall physical function than was the interview-based or medical record-based Charlson or Satariano indices of comorbidity.
Older breast cancer patients are able to provide information about their diseases and related symptoms that correlates well with medical record-based measures of comorbidity and displays similar patterns of predictive power. A new self-reported measure of cardiopulmonary comorbidity performs better than the medical record-based measures for predicting patient related functional outcomes.
比较基于患者访谈和基于病历的共病测量方法，及其与原发性肿瘤治疗、全因死亡率、自我报告的上身功能和总体身体功能的关系。
招募了在波士顿5家医院之一被诊断出的303例乳腺癌患者（年龄≥55岁）。通过患者访谈和病历摘要获取构建查尔森指数、萨塔里亚诺指数以及一种新的基于访谈的心肺共病指数所需的信息。这些指数单独或联合使用以预测患者的预后。
共病指数之间相互对应良好。没有共病指数能够预测死亡率或接受确定性原发性治疗的情况。新的基于访谈的心肺共病指数比基于访谈或病历的查尔森或萨塔里亚诺共病指数更能预测上身功能和总体身体功能。
老年乳腺癌患者能够提供与基于病历的共病测量方法相关性良好且具有相似预测能力模式的疾病及相关症状信息。一种新的自我报告的心肺共病测量方法在预测患者相关功能预后方面比基于病历的测量方法表现更好。
