Firth E C, Delahunt J, Wichtel J W, Birch H L, Goodship A E
Department of Veterinary Clinical Sciences, Massey University, Palmerston North, New Zealand.
Equine Vet J. 1999 Mar;31(2):111-5. doi: 10.1111/j.2042-3306.1999.tb03802.x.
This study was performed to test the hypothesis that a localised bone hypertrophy could occur within the subchondral cancellous architecture of the third and radial carpal bones. Using 2 levels of controlled and defined exercise, it was observed that a high intensity treadmill exercise protocol resulted in functional adaptation of the carpal bones. The increase in trabecular thickening and density was seen to be localised to those regions underlying common sites of cartilage degradation, the interface of the thickened trabeculae with the normal architecture in the third carpal bone was coincident with a common site of clinical fractures. The bone changes were determined both qualitatively on examination of slab radiographs and quantified by dual energy x-ray absorptiometry. The findings from this study are relevant to mechanical factors involved in the pathophysiology of joint degeneration. The potential clinical implications of this study are in relation to changes in the type and duration of exercise regimens used in training of equine athletes. The rapid response of bone to mechanical stimulation has implications in the longer term for localised cartilage degradation. Imaging techniques could be developed to monitor these early bone changes in the specific areas identified in this study and thus allow appropriate changes in training intensity to minimise subsequent damage to the articular surface.
本研究旨在验证一个假设，即第三腕骨和桡侧腕骨的软骨下松质骨结构内可能会出现局部骨肥大。通过2种水平的可控且明确的运动，观察到高强度跑步机运动方案导致腕骨出现功能适应性变化。小梁增厚和密度增加被发现局限于软骨退变常见部位下方的区域，第三腕骨中增厚的小梁与正常结构的界面与临床骨折的常见部位一致。通过对平板X光片的检查对骨变化进行定性测定，并通过双能X线吸收法进行定量测定。本研究的结果与关节退变病理生理学中涉及的力学因素相关。本研究的潜在临床意义与用于训练马运动员的运动方案的类型和持续时间的变化有关。骨对机械刺激的快速反应从长远来看对局部软骨退变有影响。可以开发成像技术来监测本研究确定的特定区域的这些早期骨变化，从而允许适当改变训练强度，以尽量减少随后对关节表面的损伤。
