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一例原发性肝细胞癌患者,在成功切除原发灶后发生骨转移,对放疗有反应。

A case of hepatocellular carcinoma with bone metastasis responding to radiotherapy after successful hepatectomy of primary lesion.

作者信息

Asahara T, Dohi K, Hino H, Nakahara H, Katayama K, Itamoto T, Shimamoto F, Honke Y

机构信息

Department of Surgery II, Hiroshima University School of Medicine, Japan.

出版信息

Hiroshima J Med Sci. 1999 Mar;48(1):35-9.

Abstract

Radical hepatectomy was carried out on a patient with hepatocellular carcinoma (HCC) located in segment VIII of the liver. The patient was a 56-year-old man who showed positive for hepatitis C antibody and negative for hepatitis B surface antigen. Six months after hepatectomy, a lumbar plane X-ray and computed tomography examination revealed bone metastases in the lumbar vertebrae. The patient was subsequently treated by radiation to the lumbar vertebrae in response to lumbago. The metastatic lesion has been well controlled by radiotherapy on an outpatient basis with no recurrence for 5 years and 3 months. The prognosis of patients with HCC with distant metastases is poor. It is believed that the long survival of this patient can be attributed to successful radiotherapy of the bone metastasis after hepatectomy and the lack of recurrence in the liver.

摘要

对一名肝细胞癌(HCC)位于肝脏Ⅷ段的患者实施了根治性肝切除术。该患者为一名56岁男性,丙型肝炎抗体呈阳性,乙肝表面抗原呈阴性。肝切除术后6个月,腰椎平面X线和计算机断层扫描检查显示腰椎有骨转移。随后,针对腰痛,该患者接受了腰椎放疗。通过门诊放疗,转移病灶得到了良好控制,5年零3个月未复发。伴有远处转移的HCC患者预后较差。据信,该患者的长期生存可归因于肝切除术后骨转移的成功放疗以及肝脏未复发。

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