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刚果锥虫产生的毒性活性。

The generation of toxic activity from trypanosoma congolense.

作者信息

Tizard I R, Holmes W L

出版信息

Experientia. 1976 Dec 15;32(12):1533-4. doi: 10.1007/BF01924436.

DOI:10.1007/BF01924436
PMID:1021440
Abstract

Trypanosoma congolense organism, on incubation at 20 degrees C for 91/2h, were found to generate phospholipase like activity which was capable of mediating lysis of both nucleated cells and erythrocytes as well as acute inflammatory response on intradermal inoculation.

摘要

刚果锥虫在20摄氏度下孵育9.5小时后，被发现能产生类似磷脂酶的活性，这种活性能够介导有核细胞和红细胞的裂解，以及皮内接种后的急性炎症反应。

相似文献

1
The generation of toxic activity from trypanosoma congolense.刚果锥虫产生的毒性活性。
Experientia. 1976 Dec 15;32(12):1533-4. doi: 10.1007/BF01924436.
2
The generation and identification of the hemolysin of Trypanosoma congolense.刚果锥虫溶血素的产生与鉴定
Experientia. 1977 Jul 15;33(7):901-2. doi: 10.1007/BF01951271.
3
The generation of phospholipase A and hemolytic fatty acids by autolysing suspensions of Trypanosoma congolense.
Tropenmed Parasitol. 1978 Mar;29(1):127-33.
4
In vitro erythrophagocytosis by cultured macrophages stimulated with extraneous substances and those isolated from the blood, spleen and bone marrow of Boran and N'Dama cattle infected with Trypanosoma congolense and Trypanosoma vivax.用外来物质刺激培养的巨噬细胞以及从感染刚果锥虫和活泼锥虫的博拉牛和恩达马牛的血液、脾脏和骨髓中分离出的巨噬细胞进行体外红细胞吞噬作用。
Onderstepoort J Vet Res. 2000 Dec;67(4):273-87.
5
Injury induced by Trypanosoma congolense adhesion to cell membranes.刚果锥虫粘附细胞膜诱导的损伤
J Parasitol. 1980 Feb;66(1):34-7.
6
Maintenance of infectivity of Trypanosoma congolense in vitro with explants of infected skin at 37 degrees C.
Trans R Soc Trop Med Hyg. 1979;73(4):406-8. doi: 10.1016/0035-9203(79)90164-0.
7
Effects of temperature and bovine serum albumin on lysis of erythrocytes induced by dilauroylglycerophosphocholine and didecanoylglycerophosphocholine.
Biochim Biophys Acta. 1977 Jun 2;467(2):137-45. doi: 10.1016/0005-2736(77)90191-2.
8
Development of local skin reactions in rabbits infected with metacyclic forms of Trypanosoma congolense cultured in vitro.
Ann Trop Med Parasitol. 1981 Oct;75(5):563-4. doi: 10.1080/00034983.1981.11687482.
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Dose and stage dependency for the development of local skin reactions caused by Trypanosoma congolense in goats.冈比亚锥虫引起山羊局部皮肤反应的剂量和阶段依赖性
Acta Trop. 1987 Sep;44(3):303-14.
10
Susceptibility of inbred strains of mice to Trypanosoma congolense: correlation with changes in spleen lymphocyte populations.近交系小鼠对刚果锥虫的易感性：与脾脏淋巴细胞群体变化的相关性。
Clin Exp Immunol. 1978 Apr;32(1):25-40.

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MIF-Mediated Hemodilution Promotes Pathogenic Anemia in Experimental African Trypanosomosis.巨噬细胞移动抑制因子介导的血液稀释促进实验性非洲锥虫病中的致病性贫血。

本文引用的文献

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The cattle trypanosomiases: some considerations of pathology and immunity.
Ann Trop Med Parasitol. 1950 Apr;44(1):42-54. doi: 10.1080/00034983.1950.11685428.
2
The action of snake venoms on surface films.蛇毒对表面膜的作用。
Biochem J. 1935 Feb;29(2):437-44. doi: 10.1042/bj0290437.
3
The structure of the naturally occurring phosphoglycerides. III. Action of moccasin-venom phospholipase A on ovolecithin and related substances.天然存在的磷酸甘油酯的结构。III. 噬鱼蛇毒磷脂酶A对卵黄卵磷脂及相关物质的作用。
PLoS Pathog. 2016 Sep 15;12(9):e1005862. doi: 10.1371/journal.ppat.1005862. eCollection 2016 Sep.
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The pathogenesis of experimentally induced Trypanosoma brucei infection in the dog. I. Tissue and organ damage.犬实验性布氏锥虫感染的发病机制。I. 组织和器官损伤。
Am J Pathol. 1981 Feb;102(2):168-81.
5
The generation and identification of the hemolysin of Trypanosoma congolense.刚果锥虫溶血素的产生与鉴定
Experientia. 1977 Jul 15;33(7):901-2. doi: 10.1007/BF01951271.
6
Mitogenicity of autolysates of Trypanosoma congolense.
Experientia. 1978 Jan 15;34(1):127-9. doi: 10.1007/BF01921943.
7
Biologically active products from African Trypanosomes.来自非洲锥虫的生物活性产物。
Microbiol Rev. 1978 Dec;42(4):664-81. doi: 10.1128/mr.42.4.664-681.1978.
8
Increased susceptibility of Trypanosoma lewisi infected, or decomplemented rats to Salmonella typhimurium.感染了刘易斯锥虫或补体缺失的大鼠对鼠伤寒沙门氏菌的易感性增加。
Experientia. 1978 Jan 15;34(1):118-9. doi: 10.1007/BF01921937.
Biochem J. 1957 Feb;65(2):382-9. doi: 10.1042/bj0650382.
4
Vascular reactions to histamine, histamine-liberator and leukotaxine in the skin of guinea-pigs.组胺、组胺释放剂和白细胞趋化因子对豚鼠皮肤的血管反应
J Physiol. 1952 Oct;118(2):228-57. doi: 10.1113/jphysiol.1952.sp004789.
5
In vivo effects of Clostridium welchii lecithinase.魏氏梭菌卵磷脂酶的体内效应
Surg Gynecol Obstet. 1952 Oct;95(4):465-71.
6
Trypanosoma gambiense and T. lewisi: increased vascular permeability and skin lesions in rabbits.
Exp Parasitol. 1969 Oct;26(2):214-23. doi: 10.1016/0014-4894(69)90115-5.
7
Isolation of salivarian trypanosomes from man and other mammals using DEAE-cellulose.使用二乙氨基乙基纤维素从人和其他哺乳动物中分离涎源性锥虫。
Exp Parasitol. 1970 Dec;28(3):521-34. doi: 10.1016/0014-4894(70)90120-7.
8
Letter: Release of biologically active material from dying Trypanosoma congolense in rats.
Trans R Soc Trop Med Hyg. 1973;67(6):885. doi: 10.1016/0035-9203(73)90023-0.
9
Chromatographic evidence for the synthesis of possible sleep-mediators in Trypanosoma brucei gambiense.
Experientia. 1973 Dec;29(12):1563-5. doi: 10.1007/BF01943919.
10
Pathogenesis of the anemia in african trypanosomiasis: characterization and purification of a hemolytic factor.
Schweiz Med Wochenschr. 1975 Nov 22;105(47):1582-3.