Feleke Y, Abdulkadir J
Department of Internal Medicine, Faculty of Medicine, Addis Ababa University.
Ethiop Med J. 1998 Apr;36(2):93-9.
The reliability of urine glucose testing to monitor diabetic control was investigated in patients attending the Diabetic Clinic of the Tikur Anbassa Hospital in Addis Ababa between October 1994 and January 1995 with the aim of utilising it for those with a normal renal threshold who cannot afford the cost of home blood glucose monitoring. Clinically important fasting blood glucose values were taken as those > 180 mg/dl and important urine glucose values as those > or = 0.25% by Clinitest. Capillary blood glucose was determined by visual and metre readings. Urine was tested for glucose by the standard Clinitest method. There were 265 patients, 126 IDDM and 139 NIDDM. Urine glucose corresponded satisfactorily with FBG in 80% of the patients. The sensitivity, specificity, positive and negative predictive values of urine glucose results by Clinitest in comparison with FBG by metre determination were 71%, 90%, 90% and 70% and by visual determination 71%, 86%, 80%, 79% respectively. On the basis of these results we conclude that urine glucose testing by Clinitest provides reliable information in more than 70% of our diabetic patients the majority of whom cannot afford the cost of home blood glucose monitoring.
1994年10月至1995年1月期间,在亚的斯亚贝巴提库尔·安巴萨医院糖尿病门诊就诊的患者中,对尿糖检测用于监测糖尿病控制情况的可靠性进行了调查,目的是将其用于那些肾阈值正常但负担不起家庭血糖监测费用的患者。临床上重要的空腹血糖值为>180mg/dl,重要的尿糖值为Clinitest法测定>或=0.25%。采用目视和血糖仪读数法测定毛细血管血糖。采用标准Clinitest法检测尿糖。共有265例患者,其中126例为胰岛素依赖型糖尿病(IDDM),139例为非胰岛素依赖型糖尿病(NIDDM)。80%的患者尿糖与空腹血糖(FBG)相符。与通过血糖仪测定的FBG相比,Clinitest法检测尿糖结果的敏感性、特异性、阳性预测值和阴性预测值分别为71%、90%、90%和70%;通过目视测定分别为71%、86%、80%和79%。基于这些结果,我们得出结论,Clinitest法检测尿糖能为70%以上的糖尿病患者提供可靠信息,其中大多数患者负担不起家庭血糖监测费用。