McCue J D, Gal P, Pearson R C
Internal Medicine Teaching Program, Moses H. Cone Memorial Hospital, Greensboro, North Carolina 27401.
Diabetes Care. 1983 Sep-Oct;6(5):504-5. doi: 10.2337/diacare.6.5.504.
The possibility that three new penicillins (mezlocillin, pipericillin, and azlocillin) and two new cephalosporins (ceftazidime and cefoperazone) might give false positive urine glucose testing results was studied. High and low concentrations of antibiotics were dissolved in urine and tested with Clinitest (Ames Division, Miles Laboratories, Elkhart, Indiana) and Tes-Tape (Eli Lilly and Company, Indianapolis, Indiana) at four different concentrations of glucose. None of the antibiotics interfered with the accuracy of Tes-Tape readings. All antibiotics interfered with Clinitest readings; the greatest interference was noted at high concentrations of antibiotics and low concentrations of glucose, and with the two cephalosporins. A summary of all reported cephalosporin interactions with Clinitest urine glucose testing is included.
研究了三种新型青霉素（美洛西林、哌拉西林和阿洛西林）以及两种新型头孢菌素（头孢他啶和头孢哌酮）可能导致尿糖检测结果呈假阳性的可能性。将高浓度和低浓度的抗生素溶解在尿液中，并使用Clinitest（迈尔斯实验室艾姆斯分部，印第安纳州埃尔克哈特）和Tes-Tape（礼来公司，印第安纳州印第安纳波利斯）在四种不同葡萄糖浓度下进行检测。没有一种抗生素干扰Tes-Tape读数的准确性。所有抗生素均干扰Clinitest读数；在抗生素高浓度、葡萄糖低浓度以及两种头孢菌素的情况下，干扰最为明显。文中还总结了所有已报道的头孢菌素与Clinitest尿糖检测的相互作用。
