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[伊维菌素对致倦库蚊和鳞状蚋的全身作用]

[Systemic action of ivermectin on Culex quinquefasciatus and Simulium squamosum].

作者信息

Chandre F, Hougard J M

机构信息

IRD (ex-ORSTOM)/LIN, Montpellier, France.

出版信息

Bull Soc Pathol Exot. 1999 Feb;92(1):71-2.

PMID:10214528
Abstract

The mortality of Culex quinquefasciatus mosquitoes having fed ten days earlier on a chicken treated by 2,000 micrograms/kg of ivermectin (about ten times the therapeutic dosage) is about 25% higher than the mortality recorded on mosquitoes having fed on a non treated chicken. This systemic effect occurs only if the blood meal takes place between 7 and 31 hours after the administration of the drug. However, no systemic effect is recorded either with the C. quinquefasciatus mosquito or with the Simulium squamosum black fly when they are fed on human beings treated at the therapeutic dose.

摘要

十天前吸食了用2000微克/千克伊维菌素(约为治疗剂量的十倍)处理过的鸡的血液的致倦库蚊的死亡率,比吸食未处理鸡的血液的蚊子的死亡率高出约25%。只有在给药后7至31小时之间进行吸血时,才会出现这种全身效应。然而,当致倦库蚊或鳞跗蚋吸食接受治疗剂量治疗的人类的血液时,未记录到全身效应。

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