Sulica R L, Wenig B M, Debo R F, Sessions R B
Department of Otolaryngology-Head and Neck Surgery, Georgetown University Medical Center, Washington, DC 20007, USA.
Ann Otol Rhinol Laryngol. 1999 Apr;108(4):392-7. doi: 10.1177/000348949910800413.
Sixteen cases of schneiderian-type mucosal papillomas arising in the nasopharynx and oropharynx are reported. The patients include 11 men and 5 women ranging in age from 45 to 79 years (median 62 years). In 12 patients, the papilloma was discovered as an incidental finding, and 2 patients complained of nasal airway obstruction. In the remaining 2 cases, information regarding the cause that led to discovery was unavailable. None of the patients had a prior or concurrent history of sinonasal (schneiderian) papillomas. Histologically, all of the tumors were identical to sinonasal inverted papillomas. Transnasal or transoral surgical excision was the treatment of choice. In 4 of the patients, recurrent tumor occurred within 6 months of initial resection, necessitating additional surgery. Extended follow-up information was available in 9 cases. Eight of the 9 patients are alive and have been free of disease over periods ranging from 15 to 201 months (median 114 months) from diagnosis. One patient was found to have a separate nasopharyngeal squamous cell carcinoma 14 months after the diagnosis of the schneiderian-type papilloma. This patient died secondary to the squamous cell carcinoma 30 months after his initial evaluation.
报告了16例发生于鼻咽部和口咽部的施奈德型黏膜乳头状瘤。患者包括11名男性和5名女性，年龄在45至79岁之间（中位年龄62岁）。12例患者的乳头状瘤是偶然发现的，2例患者主诉鼻气道阻塞。其余2例患者，导致发现的原因信息不详。所有患者既往均无鼻窦（施奈德型）乳头状瘤病史，也无并发鼻窦（施奈德型）乳头状瘤病史。组织学上，所有肿瘤均与鼻窦内翻性乳头状瘤相同。经鼻或经口手术切除是首选治疗方法。4例患者在初次切除后6个月内出现肿瘤复发，需要再次手术。9例患者有延长的随访信息。9例患者中的8例存活，自诊断以来无病生存期为15至201个月（中位114个月）。1例患者在施奈德型乳头状瘤诊断14个月后被发现患有独立的鼻咽部鳞状细胞癌。该患者在初次评估30个月后死于鳞状细胞癌。
