镉抗性基因座与小鼠12号染色体上基因座的连锁关系。
Linkage of the cadmium resistance locus to loci on mouse chromosome 12.
作者信息
Taylor B A
出版信息
J Hered. 1976 Nov-Dec;67(6):389-90. doi: 10.1093/oxfordjournals.jhered.a108759.
Abstract
The autosomal recessive gene cdm that confers resistance to cadmium-induced testicular necrosis in certain inbred strains of mice has been mapped on Chromosome 12 near varitint-waddler (Va). A 3-point cross involving Va, cdm, and amylase-1 (Amy-1) indicated the following gene order and approximate distances: Va-8-cdm-17-Amy-1. The cdm locus is the first polymorphic locus to be placed on Chromosome 12.
摘要
常染色体隐性基因cdm可使某些近交系小鼠对镉诱导的睾丸坏死产生抗性，该基因已被定位在第12号染色体上靠近变灰-蹒跚（Va）的位置。一项涉及Va、cdm和淀粉酶-1（Amy-1）的三点杂交表明了以下基因顺序和大致距离：Va-8-cdm-17-Amy-1。cdm基因座是第一个被定位到第12号染色体上的多态性基因座。
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