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小鼠唾液淀粉酶合成速率的遗传变异。

Genetic variation in mouse salivary amylase rate of synthesis.

作者信息

Hjorth J P

出版信息

Biochem Genet. 1979 Aug;17(7-8):665-82. doi: 10.1007/BF00502125.

DOI:10.1007/BF00502125
PMID:94264
Abstract

Heterozygotes from matings of the mouse strains YBR/Cv and C3H/As have about 3 times more YBR-amylase than C3H-amylase in the saliva. The determinant for this quantitative effect is located on linkage group XVI close to or with in the structural gene for salivary amylase. The quantitative effect is the result of an increase in the rate of synthesis of YBR-amylase, and the determinant is cis acting. Studies of other mouse strains suggest that regulatory genetic elements may modulate salivary amylase production.

摘要

小鼠品系YBR/Cv和C3H/As杂交产生的杂合子,其唾液中YBR淀粉酶的含量约为C3H淀粉酶的3倍。这种数量效应的决定因素位于第十六连锁群上,靠近唾液淀粉酶的结构基因或与之相连。数量效应是YBR淀粉酶合成速率增加的结果,且该决定因素具有顺式作用。对其他小鼠品系的研究表明,调控基因元件可能会调节唾液淀粉酶的产生。

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1
Genetic variation in mouse salivary amylase rate of synthesis.小鼠唾液淀粉酶合成速率的遗传变异。
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2
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Genetics. 1982 May;101(1):91-102. doi: 10.1093/genetics/101.1.91.
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Multiple structural genes for mouse amylase.小鼠淀粉酶的多个结构基因。
Biochem Genet. 1980 Apr;18(3-4):281-302. doi: 10.1007/BF00484242.
9
Multiple non-allelic genes encoding pancreatic alpha-amylase of mouse are expressed in a strain-specific fashion.编码小鼠胰腺α-淀粉酶的多个非等位基因以品系特异性方式表达。
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Interstrain variation in amylase gene copy number and mRNA abundance in three mouse tissues.三种小鼠组织中淀粉酶基因拷贝数和mRNA丰度的品系间差异。
Genetics. 1986 Jul;113(3):713-22. doi: 10.1093/genetics/113.3.713.
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4
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Genetics. 1980 May;95(1):129-41. doi: 10.1093/genetics/95.1.129.
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Haemoglobin polymorphism of cod in the Baltic and the Danish Belt Sea.波罗的海和丹麦海峡鳕鱼的血红蛋白多态性
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Genetic studies of the amylase isoenzymes of the bank vole, Clethrionomys glareola.小林姬鼠淀粉酶同工酶的遗传学研究
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