Novey H S, Wells I D
Am J Clin Pathol. 1978 Nov;70(5):840-3. doi: 10.1093/ajcp/70.5.840.
A case with the characteristics of allergic bronchopulmonary aspergillosis is described. The species of Aspergillus involved, A. ochraceus, has not previously been found in this disorder. The organism had antigenic properties distinct from five other species of Aspergillus most commonly associated with allergic bronchopulmonary aspergillosis. The patient had immediate skin test, immunodiffusion, and radioallergosorbent reactivity to the species. Four per cent of 112 serum samples from others suspected of having allergic bronchopulmonary aspergillosis had precipitins to A. ochraceus only. It may be necessary in some cases to prepare and test extracts of the patient's Aspergillus isolate in order to confirm the diagnosis.
描述了一例具有变应性支气管肺曲霉病特征的病例。所涉及的曲霉属菌种为赭曲霉,此前在该疾病中尚未发现过。该生物体具有与其他五种最常与变应性支气管肺曲霉病相关的曲霉属菌种不同的抗原特性。患者对该菌种有即刻皮肤试验、免疫扩散和放射变应原吸附反应。在112份疑似患有变应性支气管肺曲霉病的其他患者的血清样本中,有4%仅对赭曲霉产生沉淀素。在某些情况下,可能有必要制备并检测患者分离出的曲霉提取物以确诊。