Perez M T, Suster S
Arkadi M. Rywlin Department of Pathology, Mount Sinai Medical Center of Greater Miami and the University of Miami School of Medicine, Florida, USA.
Am J Dermatopathol. 1999 Apr;21(2):181-4. doi: 10.1097/00000372-199904000-00014.
Balloon cells are altered melanocytes with clear vacuolated cytoplasm caused by a defect in the process of melanogenesis. Although rare, balloon cell change has been observed in a variety of melanocytic proliferations, particularly intradermal melanocytic nevi and melanoma. When present, such features may lead to difficulties in diagnosis, particularly with other clear cell neoplasms. We report an unusual case of the development of balloon cell change in a cellular blue nevus, a phenomenon that has not been extensively addressed in the literature. The importance of recognizing this change in cellular blue nevus to avoid misinterpreting the lesion as malignant is discussed.
气球样细胞是黑素细胞发生改变，其细胞质因黑素生成过程中的缺陷而出现透明的空泡。尽管罕见，但在多种黑素细胞增殖性病变中均观察到气球样细胞改变，尤其是皮内黑素细胞痣和黑色素瘤。当出现这种情况时，这些特征可能会导致诊断困难，尤其是与其他透明细胞肿瘤鉴别时。我们报告了1例细胞性蓝痣出现气球样细胞改变的罕见病例，这一现象在文献中尚未得到广泛探讨。本文讨论了认识细胞性蓝痣中这种改变以避免将病变误诊为恶性病变的重要性。
