Katz Gabriel, Blum Sharon, Leeva Omer, Axer-Siegel Ruth, Moisseiev Joseph, Tesler Gili, Ehrlich Rita
Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, 52621, Israel.
Ophthalmology Department, Rabin Medical Center, Petah Tikva, Israel.
Graefes Arch Clin Exp Ophthalmol. 2015 Oct;253(10):1729-33. doi: 10.1007/s00417-015-3009-z. Epub 2015 Apr 24.
The European Society of Cataract & Refractive Surgeons (ESCRS) study reported a decrease in endophthalmitis rates from 0.34 % to 0.08 % with the use of intracameral cefuroxime. The purpose of this study was to compare the endophthalmitis rates before and after the introduction of intracameral cefuroxime (ICC) routinely at the end of cataract surgery.
A retrospective consecutive cohort study. We compared the rates of endophthalmitis between the years 2000-2006, and the years 2007-2014, after the pivotal publication of the ESCRS. Data collected included age, gender, culture results, initial and final visual acuity, and complications. Only patients that presented with endophthalmitis following cataract surgery performed at the two centers were included.
Twenty-two cases of endophthalmitis occurred between the years 2000 and 2006, out of 26,663 cataract operations performed at the two centers, a rate of 0.083 %. Ten cases occurred between the years 2007 and 2014 out of 29,431 cataract operations, a rate of 0.034 %. The difference was statistically significant (p = 0.03) CONCLUSIONS: The introduction of prophylactic use of intracameral cefuroxime was associated with a significant reduction in post-operative endophthalmitis rates in our centers. We strongly recommend adoption of this routine by for all cataract operations except when contraindicated.
欧洲白内障与屈光手术医师学会（ESCRS）的研究报告称，使用前房内注射头孢呋辛后眼内炎发生率从0.34%降至0.08%。本研究的目的是比较在白内障手术结束时常规引入前房内注射头孢呋辛（ICC）前后的眼内炎发生率。
一项回顾性连续队列研究。我们比较了ESCRS关键研究发表后的2000 - 2006年以及2007 - 2014年的眼内炎发生率。收集的数据包括年龄、性别、培养结果、初始和最终视力以及并发症。仅纳入在这两个中心进行白内障手术后发生眼内炎的患者。
在2000年至2006年期间，两个中心进行的26,663例白内障手术中有22例发生眼内炎，发生率为0.083%。在2007年至2014年期间，29,431例白内障手术中有10例发生眼内炎，发生率为0.034%。差异具有统计学意义（p = 0.03）。结论：在我们中心，预防性使用前房内注射头孢呋辛与术后眼内炎发生率的显著降低相关。我们强烈建议除有禁忌证外，所有白内障手术均采用这一常规操作。
