Mega Andrea, Marzi Luca, Kob Michael, Piccin Andrea, Floreani Annarosa
Gastroenterology Department, Bolzano Regional Hospital, 39100 Bolzano, Italy.
Dietetics and Clinical Nutrition Unit, Bolzano Regional Hospital, 39100 Bolzano, Italy.
Nutrients. 2021 Apr 16;13(4):1326. doi: 10.3390/nu13041326.
The liver is an important organ and plays a key role in the regulation of metabolism and in the secretion, storage, and detoxification of endogenous and exogenous substances. The impact of food and nutrition on the pathophysiological mechanisms of liver injury represents a great controversy. Several environmental factors including food and micronutrients are involved in the pathogenesis of liver damage. Conversely, some xenobiotics and micronutrients have been recognized to have a protective effect in several liver diseases. This paper offers an overview of the current knowledge on the role of xenobiotics and micronutrients in liver damage.
肝脏是一个重要器官，在新陈代谢调节以及内源性和外源性物质的分泌、储存及解毒过程中发挥关键作用。食物和营养对肝损伤病理生理机制的影响存在很大争议。包括食物和微量营养素在内的多种环境因素参与了肝损伤的发病机制。相反，一些外源性物质和微量营养素已被认为在几种肝脏疾病中具有保护作用。本文概述了目前关于外源性物质和微量营养素在肝损伤中作用的相关知识。
