Ooka A A, Kuhar K A, Cho N, Garrell R L
Department of Chemistry and Biochemistry, University of California at Los Angeles, 90095-1569, USA.
Biospectroscopy. 1999;5(1):9-17. doi: 10.1002/(SICI)1520-6343(1999)5:1<9::AID-BSPY3>3.0.CO;2-T.
Surface enhanced Raman spectroscopy (SERS) was used to characterize a homologous series of alpha,omega-amino acids on colloidal gold and silver. Raman and SER spectra of the alpha,omega-amino acids, NH2(CH2)nCOOH (n = 3-7), are presented and analyzed, revealing the probable conformations of the molecules on the metal surfaces. The alpha,omega-amino acids interact with silver and gold through both the amine and carboxylate end groups, and modify the conformation of the molecular backbone in order to maximize these interactions. An odd-even effect is observed for backbone conformations of molecules adsorbed to the silver substrate. The anomolous SER spectrum of 5-aminopentanoic acid on gold suggests the possibility of condensation polymerization at the gold surface.
表面增强拉曼光谱（SERS）用于表征胶体金和银上的一系列同系α,ω-氨基酸。给出并分析了α,ω-氨基酸NH2(CH2)nCOOH（n = 3 - 7）的拉曼光谱和表面增强拉曼光谱，揭示了分子在金属表面可能的构象。α,ω-氨基酸通过胺基和羧基端基与银和金相互作用，并改变分子主链的构象以最大化这些相互作用。在吸附于银基底的分子主链构象中观察到奇偶效应。5-氨基戊酸在金上的异常表面增强拉曼光谱表明在金表面发生缩聚反应的可能性。
