Urman J D, Bobrove A M
Department of Medicine, Kaiser Permanente Medical Center, Mountain View, California, USA.
Arch Intern Med. 1999 Apr 26;159(8):877-8. doi: 10.1001/archinte.159.8.877.
Gustatory sweating is a more common manifestation of diabetes mellitus than is appreciated. It is a distressing problem that has been difficult to treat safely.
Daily topical application of glycopyrrolate roll-on lotion was offered as an alternative to oral anticholinergic agents to an 87-year-old woman with long-standing type 2 diabetes mellitus who complained of profuse sweating after eating.
Gustatory sweating was relieved by application of glycopyrrolate and reappeared when the glycopyrrolate was briefly withdrawn to confirm its therapeutic effect.
For moderate to severe symptoms of diabetic gustatory sweating, topical application of glycopyrrolate is safe, effective, well tolerated, and convenient.
味觉性出汗在糖尿病中是一种比人们所认识到的更为常见的表现。它是一个令人苦恼的问题，一直难以安全地治疗。
对于一位患有长期2型糖尿病且抱怨进食后大量出汗的87岁女性，提供每日外用格隆溴铵滚涂洗剂作为口服抗胆碱能药物的替代方案。
应用格隆溴铵后味觉性出汗得到缓解，当短暂停用格隆溴铵以确认其治疗效果时，出汗又再次出现。
对于糖尿病性味觉性出汗的中至重度症状，外用格隆溴铵是安全、有效、耐受性良好且方便的。
