Atkin S L, Brown P M
Scarborough General Hospital, UK.
Diabet Med. 1996 May;13(5):493-4. doi: 10.1002/(SICI)1096-9136(199605)13:5<493::AID-DIA62>3.0.CO;2-Q.
A 42-year-old insulin-dependent diabetic man presented with severe bilateral gustatory sweating associated with a deterioration in his glycaemic control. Conventional oral antimuscarinic medication was contraindicated because of his cardiac insufficiency. Topical 0.5% glycopyrrolate cream was tried and applied on alternate days to his face, which resulted in the complete cessation of his gustatory sweating without side-effects. Topical glycopyrrolate cream is an effective treatment of diabetic gustatory sweating without the adverse effects commonly found with oral anti-muscarinic medication.
一名42岁的胰岛素依赖型糖尿病男性患者,出现严重的双侧味觉性出汗,同时血糖控制恶化。由于他存在心脏功能不全,常规口服抗胆碱能药物是禁忌的。尝试使用0.5%的格隆溴铵乳膏局部外用,隔天涂抹于面部,结果味觉性出汗完全停止,且无副作用。局部使用格隆溴铵乳膏是治疗糖尿病性味觉性出汗的有效方法,不会产生口服抗胆碱能药物常见的不良反应。