Audette G F, Zoghaib W M, Gupta S V, Quail J W, Delbaere L T
Department of Biochemistry, University of Saskatchewan, Saskatoon, Canada.
Acta Crystallogr C. 1999 Mar 15;55 ( Pt 3):427-30. doi: 10.1107/s0108270198013249.
In the title compound, C13H21N3O5, the pyrimidine ring adopts the antiperiplanar (-ap) conformation [chi = 193.54 (19) degrees]. The deoxyribose sugar ring has the C2'-exo-C3'-endo (2T3) twist conformation. The pseudo-rotational parameters of the deoxyribose sugar ring are P = 6.83 (2) degrees and Tm = 38.27 (2) degrees. The exocyclic side chain at C5' has the g+ conformation [gamma = 47.7 (3) degrees]. The 5-methoxymethyl group is distal to the deoxyribose sugar ring, with a C6-C5-C52-O52 torsion angle of -91.9 (3) degrees.
在标题化合物C₁₃H₂₁N₃O₅中，嘧啶环采取反叠构象（χ = 193.54 (19)°）。脱氧核糖糖环具有C2'-外向-C3'-内向（2T3）扭转构象。脱氧核糖糖环的假旋转参数为P = 6.83 (2)°和Tm = 38.27 (2)°。C5'处的环外侧链具有g⁺构象（γ = 47.7 (3)°）。5-甲氧基甲基基团与脱氧核糖糖环远端，C6-C5-C52-O52扭转角为-91.9 (3)°。
