Manoharan S, Kavitha K, Nagini S
Department of Biochemistry, Faculty of Science, Annamalai University, Annamalainagar.
Indian J Physiol Pharmacol. 1997 Jan;41(1):62-6.
The present study has examined the role of life-style on plasma and erythrocyte membrane lipid profile in 25 adult male gastric cancer patients as well as age and sex-matched controls. Total, free and LDH cholesterol were markedly elevated in plasma and erythrocyte membrane whereas HDL cholesterol and triglycerides were significantly reduced in gastric cancer patients. These changes can be attributed to alcohol consumption and cigarette smoking-risk factors in gastric carcinogenesis, associated with low levels of ascorbic acid and vitamin E.
本研究调查了生活方式对25名成年男性胃癌患者以及年龄和性别匹配的对照组的血浆和红细胞膜脂质谱的影响。胃癌患者血浆和红细胞膜中的总胆固醇、游离胆固醇和乳酸脱氢酶胆固醇显著升高，而高密度脂蛋白胆固醇和甘油三酯则显著降低。这些变化可归因于酒精消费和吸烟——胃癌发生中的危险因素，与抗坏血酸和维生素E水平低有关。
