Arivazhagan S, Kavitha K, Nagini S
Department of Biochemistry, Faculty of Science, Annamalai University, Annamalainagar.
Indian J Physiol Pharmacol. 1998 Jan;42(1):123-6.
The present study has examined the glycoconjugate profile in plasma and erythrocyte membranes of 24 adult male gastric cancer patients and an equal number of age and sex-matched controls. Protein-bound hexose, hexosamine and sialic acid were significantly increased in plasma and erythrocytes of gastric cancer patients compared to controls. Elevation of glycoconjugates in circulation is suggested to be a result of increased shedding by the tumor cells or increased synthesis by liver, due to acute phase response.
本研究检测了24名成年男性胃癌患者以及同等数量年龄和性别匹配的对照者血浆和红细胞膜中的糖缀合物谱。与对照组相比，胃癌患者血浆和红细胞中的蛋白结合己糖、己糖胺和唾液酸显著增加。循环中糖缀合物的升高被认为是肿瘤细胞脱落增加或由于急性期反应导致肝脏合成增加的结果。
