Meden H, Fattahi-Meibodi A
Department of Obstetrics and Gynecology, University of Göttingen, Germany.
Int J Biol Markers. 1998 Oct-Dec;13(4):231-7. doi: 10.1177/172460089801300411.
The tumor marker CA 125 was initially thought to be specific for ovarian malignancies. Subsequently it was found to be raised in a variety of benign conditions, including pregnancy, pelvic inflammatory disease, tuberculosis and cirrhosis of the liver. With respect to gynecological tumors, CA 125 may be elevated in benign ovarian cysts, tubo-ovarian abscess, endometriosis, hyperstimulation syndrome, ectopic pregnancy and fibroids. These results demonstrate that CA 125 is a marker of non-specific peritoneal conditions.
肿瘤标志物CA 125最初被认为是卵巢恶性肿瘤的特异性标志物。随后发现它在多种良性疾病中也会升高，包括妊娠、盆腔炎、肺结核和肝硬化。就妇科肿瘤而言，CA 125在良性卵巢囊肿、输卵管卵巢脓肿、子宫内膜异位症、卵巢过度刺激综合征、宫外孕和子宫肌瘤中也可能升高。这些结果表明，CA 125是非特异性腹膜疾病的标志物。
