Carabin H, Gyorkos T W, Soto J C, Joseph L, Payment P, Collet J P
Department of Epidemiology and Biostatistics, McGill University, Montreal General Hospital, Montréal, Québec, Canada.
Epidemiology. 1999 May;10(3):219-27.
The objective of this study was to assess the effectiveness of a hygiene program in reducing the incidence of respiratory and diarrheal diseases in toddlers attending day care centers. A randomized field trial was conducted in 52 day care centers in Quebec, Canada, between September 1, 1996 and November 30, 1997. Absences for any reasons and the daily occurrence of colds and/or diarrhea in toddlers were recorded on calendars by the educators. The number of fecal coliforms on children's hands and on educators' hands was measured during three unannounced visits. Overall, 1,729 children were followed in 47 day care centers for a total of 153,643 child-days. The incidence rate of diarrhea was considerably reduced by the effect of monitoring (IRR = 0.73, 95% CI = 0.54,0.97), and the intervention reduced the incidence rate of upper respiratory tract infections (IRR = 0.80, 95% CI = 0.68,0.93). Monitoring alone also had an important effect in reducing the level of bacterial contamination on children's and educators' hands. The results indicate that both an intervention program and monitoring alone play a role in reducing infections in children attending day care centers.
本研究的目的是评估一项卫生计划在降低日托中心幼儿呼吸道疾病和腹泻疾病发病率方面的效果。1996年9月1日至1997年11月30日期间,在加拿大魁北克的52个日托中心进行了一项随机现场试验。教育工作者在日历上记录幼儿因任何原因的缺勤情况以及感冒和/或腹泻的每日发病情况。在三次突击检查中测量了儿童手部和教育工作者手部的粪大肠菌群数量。总体而言,47个日托中心的1729名儿童被跟踪观察了总计153643个儿童日。监测的效果使腹泻发病率大幅降低(发病率比=0.73,95%置信区间=0.54,0.97),并且干预措施降低了上呼吸道感染的发病率(发病率比=0.80,95%置信区间=0.68,0.93)。仅监测在降低儿童和教育工作者手部细菌污染水平方面也有重要作用。结果表明,干预计划和仅进行监测在降低日托中心儿童感染方面都发挥了作用。