关节腔内注射后发生的药物性皮肤栓塞（尼古劳综合征）

[Embolia cutis medicamentosa (Nicolau syndrome) after intra-articular injection].

作者信息

Beissert S, Presser D, Rütter A, Metze D, Luger T A, Schwarz T

机构信息

Klinik und Poliklinik für Hautkrankheiten, Westfälische Wilhelms-Universität Münster.

出版信息

Hautarzt. 1999 Mar;50(3):214-6. doi: 10.1007/s001050050892.

DOI:10.1007/s001050050892

PMID:10231693

Abstract

Embolia cutis medicamentosa (Nicolau Syndrome) is a very rare complication of intramuscular injections which presents with extensive necrosis of the injected skin area. Intra-arteria and/or para-arterial injections after prior perforation of certain vessels are discussed as possible pathogenetic mechanisms. We describe the occurrence of embolia cutis medicamentosa after intra-articular injections into the knee.

摘要

药物性皮肤栓塞（尼科劳综合征）是肌肉注射非常罕见的并发症，表现为注射部位皮肤广泛坏死。某些血管预先穿孔后进行动脉内和/或动脉旁注射被认为是可能的发病机制。我们描述了膝关节内注射后发生药物性皮肤栓塞的情况。