Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida.
作者信息
Sittie A A, Lemmich E, Olsen C E, Hviid L, Kharazmi A, Nkrumah F K, Christensen S B
出版信息
Planta Med. 1999 Apr;65(3):259-61. doi: 10.1055/s-2006-960473.
PMID:10232074
Abstract
Anthraquinones have been isolated by bioassay-guided fractionation from Morinda lucida. Structure-activity studies show that an aldehyde group at C-2 and a phenolic hydroxy group at C-3 enhance the activity of the anthraquinones against the growth of Plasmodium falciparum and promastigotes of Leishmania major in vitro.
摘要
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