一项关于海巴戟（诺丽）茎提取物及其主要成分抗利什曼原虫活性的双盲、随机临床试验。
A double-blind, randomized, clinical trial on the antileishmanial activity of a Morinda citrifolia (Noni) stem extract and its major constituents.
作者信息
Sattar Fouzia A, Ahmed Fayaz, Ahmed Nadeem, Sattar Samina A, Malghani Muhammad A K, Choudhary Muhammad I
机构信息
Balochistan University of Information Technology, Engineering and Management Sciences, Quetta, Pakistan.
出版信息
Nat Prod Commun. 2012 Feb;7(2):195-6.
A controlled study was conducted to determine the efficiency of a topical ointment prepared from the stem extract of Morinda citrifolia against cutaneous leishmaniasis. Similarly, the in vitro antileishmanial activity of morindicone and morinthone isolated from the extract were investigated against Leishmania major. These compounds displayed good activity. Out of 40 patients, 50% showed an excellent response and 30% exhibited good improvement.
开展了一项对照研究，以确定由巴戟天茎提取物制备的外用软膏治疗皮肤利什曼病的疗效。同样，对从提取物中分离出的莫林酮和莫林索宁针对硕大利什曼原虫的体外抗利什曼活性进行了研究。这些化合物显示出良好的活性。40名患者中，50%显示出极佳的反应，30%有明显改善。
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