Gil'iano N Ia, Malinovskiĭ O V
Tsitologiia. 1976 Oct;18(10):1284-8.
Effect of X-rays on DNA synthesis and mitotic activity of regenerating liver cells has been studied. The irradiation was performed at a dose of 630 rad before hepatectomy and 2.5 and 6 hours after the stimulation of liver. With the stimulated liver being irradiated, the number of cells synthetizing DNA and entering into mitosis was seen reduced almost twice, whereas DNA synthesis and entering into mitosis were delayed, resp., by 4 and 6 hours. Irradiation of liver before the stimulation brings about a delay in DNA synthesis and in start of mitosis by 2 and 4 hours, resp., without reducing the numbers of cells capable to synthesize DNA and to enter mitosis.
研究了X射线对再生肝细胞DNA合成及有丝分裂活性的影响。在肝切除术前以及刺激肝脏后2.5小时和6小时进行630拉德剂量的照射。当受刺激的肝脏受到照射时，合成DNA并进入有丝分裂的细胞数量减少了近一半，而DNA合成和进入有丝分裂分别延迟了4小时和6小时。在刺激前照射肝脏分别使DNA合成和有丝分裂开始延迟2小时和4小时，但不减少能够合成DNA并进入有丝分裂的细胞数量。
