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[抗原刺激巨噬细胞膜的构象变化]

[Conformational changes in the membranes of antigenically stimulated macrophages].

作者信息

Dumanova L

出版信息

Vet Med Nauki. 1976;13(9):65-8.

PMID:1025849
Abstract

The conformation changes taking place in the membrane of antigen-stimulated macrophages were followed up by means of serologic methods and agglutination with concavalin A. It was found that: 1. Following antigen stimulation the receptors, located in the cell membrane, are saturated with a lower amount of concavalin A than the receptors of unstimulated macrophages. 2. Antigen stimulation enhances the agglutinogenic capacity of macrophages. The conformation changes observed are discussed in brief.

摘要

通过血清学方法以及伴刀豆球蛋白A凝集反应,对抗原刺激巨噬细胞膜中发生的构象变化进行了追踪研究。结果发现:1. 抗原刺激后,位于细胞膜上的受体被伴刀豆球蛋白A饱和所需的量比未受刺激巨噬细胞的受体少。2. 抗原刺激增强了巨噬细胞的凝集能力。简要讨论了观察到的构象变化。

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