Russell W L, McKenzie M W
Hosp Formul. 1983 Jun;18(6):625-8, 631-5, 638.
A national survey of neonatal intensive care units (NICUs) was undertaken to obtain information concerning drug usage, dosages, methods of administration, incidence of drug-induced phlebitis, and drug reference sources. Antimicrobial agents are the most frequently used drugs in NICUs. Dosages reported by NICUs generally agreed with dosage recommendations by the manufacturer and literature citations. A 10% estimate of phlebitis was the consensus report by NICUs. Calcium gluconate was implicated most often as causing phlebitis, and most NICUs reported that drugs are not mixed with hyperalimentation solutions. The Pharmacy and Therapeutic Committee should review drug dosages in neonates and establish policies for intravenous drug administration methods and rates to ensure uniform initial doses and to provide a consensus among clinicians using these medications.
开展了一项针对新生儿重症监护病房（NICU）的全国性调查，以获取有关药物使用、剂量、给药方法、药物性静脉炎发生率及药物参考来源的信息。抗菌药物是新生儿重症监护病房中最常用的药物。新生儿重症监护病房报告的剂量通常与制造商的剂量建议及文献引用一致。新生儿重症监护病房的共识报告估计静脉炎发生率为10%。葡萄糖酸钙最常被认为是导致静脉炎的原因，大多数新生儿重症监护病房报告称药物不与胃肠外营养溶液混合。药学与治疗学委员会应审查新生儿用药剂量，并制定静脉给药方法和速度的政策，以确保初始剂量一致，并在使用这些药物的临床医生之间达成共识。
