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聚苯乙烯及食品中苯乙烯单体的定量分析,包括对大鼠体内该单体吸收及药效学的一些初步研究。

Quantitative analysis of styrene monomer in polystyrene and foods including some preliminary studies of the uptake and pharmacodynamics of the monomer in rats.

作者信息

Withey J R

出版信息

Environ Health Perspect. 1976 Oct;17:125-33. doi: 10.1289/ehp.7617125.

Abstract

A variety of food containers, drinking cups and cutlery, fabricated from polystyrene (PS) or polystyrene-related plastic, were analyzed for their styrene monomer content. Samples of yogurt, packaged in PS cups, were similarly analyzed and the leaching of styrene monomer from PS containers by some food simulants was also determined. Blood level studies with rats, dosed with styrene monomer by various routes, illustrated uptake phenomena that were dependent on the dose and route of administration and were also affected by the vehicle used to convey the styrene monomer.

摘要

对各种由聚苯乙烯(PS)或与聚苯乙烯相关的塑料制成的食品容器、水杯和餐具进行了苯乙烯单体含量分析。对包装在PS杯中的酸奶样品进行了类似分析,并测定了一些食品模拟物从PS容器中浸出苯乙烯单体的情况。对通过各种途径给予苯乙烯单体的大鼠进行的血药浓度研究表明,摄取现象取决于给药剂量和途径,也受用于输送苯乙烯单体的载体影响。

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